What is the treatment for a thyroglossal duct cyst?

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Last updated: April 15, 2025View editorial policy

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From the Research

The treatment of choice for a thyroglossal duct cyst is complete surgical excision via the Sistrunk procedure, as it significantly reduces recurrence rates and is considered a safe and effective procedure 1, 2.

Overview of Thyroglossal Duct Cyst Treatment

The Sistrunk procedure involves removing the cyst, the central portion of the hyoid bone, and the tract leading to the base of the tongue. This approach is recommended even for asymptomatic cysts to prevent future infection, potential malignant transformation, and cosmetic concerns.

Key Considerations

  • Preoperative evaluation should include thyroid function tests and imaging (ultrasound or CT scan) to confirm the diagnosis and ensure a normal thyroid gland is present.
  • Antibiotics may be prescribed before surgery if the cyst is infected, with surgery delayed until the infection resolves.
  • The procedure is generally performed as outpatient surgery under general anesthesia, with patients returning home the same day.
  • Potential complications include infection, hematoma, seroma, and injury to surrounding structures, but these are uncommon with experienced surgeons.

Recent Evidence

A recent study published in 2021 2 supports the use of the Sistrunk procedure as the baseline of surgical treatment for thyroglossal duct cyst carcinomas, with additional treatments such as thyroidectomy, neck dissection, and adjuvant therapy considered for high-risk lesions.

Conclusion Not Applicable - Direct Answer Only

The Sistrunk procedure is the preferred treatment for thyroglossal duct cysts, with a recurrence rate of less than 3% when performed correctly 1. Some key points to consider when performing the Sistrunk procedure include:

  • Resection of the body of the hyoid bone
  • Removal of the cyst and tract leading to the base of the tongue
  • Potential risks for recurrence, such as surgery during the inflammatory phase, cyst rupture during dissection, and technical error during the surgical procedure.

References

Research

Thyroglossal duct surgery. Sistrunk procedure.

European annals of otorhinolaryngology, head and neck diseases, 2016

Research

Evidence and controversies in management of thyroglossal duct cyst carcinoma.

Current opinion in otolaryngology & head and neck surgery, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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