What is the best course of treatment for a 15-month-old child with diarrhea and vomiting for 1 day?

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Management of a 15-Month-Old with Acute Diarrhea and Vomiting

Begin oral rehydration solution (ORS) immediately using small, frequent volumes (5 mL every 1-2 minutes via spoon or syringe), assess hydration status to determine severity, and continue breastfeeding or resume full-strength formula once rehydrated. 1, 2

Immediate Assessment of Hydration Status

Rapidly evaluate the child's hydration severity by examining:

  • Capillary refill time (most reliable predictor in this age group) 3
  • Skin turgor (pinch test for tenting) 2, 3
  • Mucous membranes (dry vs moist) 2
  • Mental status (alert vs lethargic) 1, 2
  • Pulse quality 1

Classify dehydration severity:

  • Mild (3-5% deficit): Increased thirst, slightly dry mucous membranes 2, 3
  • Moderate (6-9% deficit): Loss of skin turgor, dry mucous membranes, decreased urine output 2, 3
  • Severe (≥10% deficit): Severe lethargy, prolonged skin tenting >2 seconds, cool extremities with poor perfusion, rapid deep breathing 3

Rehydration Protocol Based on Severity

For Mild Dehydration (Most Likely in This Case)

  • Administer 50 mL/kg of ORS over 2-4 hours 1, 2
  • Use commercially available low-osmolarity ORS such as Pedialyte, CeraLyte, or Enfalac Lytren 1
  • Do NOT use apple juice, Gatorade, or soft drinks as they contain inadequate sodium and excessive osmolality that worsens diarrhea 1, 3, 4

For Moderate Dehydration

  • Administer 100 mL/kg of ORS over 2-4 hours 1, 2
  • Consider nasogastric administration if oral intake fails 1

For Severe Dehydration (Emergency)

  • Immediately administer 20 mL/kg IV boluses of Ringer's lactate or normal saline until pulse, perfusion, and mental status normalize 1, 2
  • This requires immediate emergency department evaluation 3

Managing the Vomiting

The key pitfall is allowing a thirsty child to drink large volumes rapidly, which triggers more vomiting. 1

  • Administer 5 mL of ORS every 1-2 minutes using a spoon or syringe 1, 2
  • Gradually increase the amount as tolerated 1, 2
  • Close supervision is essential to ensure slow, controlled intake 1
  • Vomiting often decreases as dehydration is corrected 1
  • If persistent vomiting prevents adequate intake, consider continuous slow nasogastric infusion 1

Replacing Ongoing Losses

After initial rehydration, replace continuing losses:

  • 10 mL/kg of ORS for each watery stool 2, 3
  • 2 mL/kg of ORS for each vomiting episode 2, 3
  • Continue this replacement until diarrhea and vomiting resolve 2

Nutritional Management

Resume feeding immediately upon rehydration—there is no benefit to "bowel rest." 1, 3

  • If breastfed: Continue breastfeeding on demand throughout the entire episode without any interruption 2, 3
  • If formula-fed: Resume full-strength formula immediately after rehydration (lactose-containing formula is tolerated in most cases) 1, 2
  • Offer age-appropriate foods including starches, cereals, yogurt, fruits, and vegetables 1, 2
  • Avoid foods high in simple sugars and fats 1, 3

Medications: What NOT to Use

Critical contraindications in this age group:

  • Antimotility drugs (loperamide) are ABSOLUTELY CONTRAINDICATED in all children under 18 years due to risks of respiratory depression and serious cardiac adverse reactions 2, 3
  • Antiemetics (ondansetron) are NOT recommended for children under 4 years of age 2
  • Antibiotics are NOT indicated for simple acute watery diarrhea unless bloody diarrhea (dysentery), high fever, or diarrhea persisting >5 days is present 1, 2

Reassessment and Red Flags

Reassess hydration status after 2-4 hours of rehydration. 2, 3

Instruct parents to return immediately if:

  • Persistent watery stools continue or worsen 2
  • Intractable vomiting develops 1, 2
  • Decreased urine output occurs 1
  • Child becomes irritable, lethargic, or condition worsens 1, 2
  • Bloody diarrhea appears 2
  • High fever develops 2

Home Management Strategy

  • Parents should keep ORS sachets at home and begin administration at the first sign of diarrhea 1, 2
  • Provide a 24-hour supply of ORS to parents at this visit 1
  • Educate on proper handwashing after diaper changes and before food preparation 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Diarrhea in Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Pediatric Diarrhea with Dehydration and Electrolyte Disturbances

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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