What are the treatment options for atrial flutter?

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Last updated: February 14, 2025View editorial policy

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From the Guidelines

Atrial flutter treatment options include catheter ablation, antiarrhythmic medications, and rate control medications.

Treatment Options

  • Catheter ablation is a recommended treatment option for patients with symptomatic atrial flutter, particularly those with CTI-dependent atrial flutter 1.
  • Antiarrhythmic medications such as amiodarone, dofetilide, and sotalol can be used to maintain sinus rhythm in patients with symptomatic, recurrent atrial flutter 1.
  • Rate control medications including beta blockers, diltiazem, and verapamil are useful for controlling the ventricular rate in patients with hemodynamically tolerated atrial flutter 1.

Specific Treatment Recommendations

  • Catheter ablation of the CTI is recommended for patients with CTI-dependent atrial flutter that is symptomatic or refractory to pharmacological rate control 1.
  • Antiarrhythmic therapy with medications such as flecainide or propafenone may be considered for patients without structural heart disease or ischemic heart disease who have symptomatic recurrent atrial flutter 1.
  • Antithrombotic therapy is recommended for patients with atrial flutter to align with recommended antithrombotic therapy for patients with AF 1.

Additional Considerations

  • Elective synchronized cardioversion is indicated in stable patients with well-tolerated atrial flutter when a rhythm-control strategy is being pursued 1.
  • Rapid atrial pacing can be useful for acute conversion of atrial flutter in patients who have pacing wires in place as part of a permanent pacemaker or implantable cardioverter-defibrillator 1.
  • Catheter ablation may be reasonable for asymptomatic patients with recurrent atrial flutter, particularly those with a high burden of atrial flutter 1.

From the Research

Treatment Options for Atrial Flutter

The treatment options for atrial flutter include:

  • Electrical cardioversion and/or antiarrhythmic medications 2, 3
  • Type I and Type III antiarrhythmic drugs to terminate or prevent recurrent episodes 3
  • Type II (beta-blockers) and Type IV (calcium channel blockers) to control the ventricular rate during atrial flutter 3
  • Radiofrequency catheter ablation to interrupt the reentrant circuit and prevent recurrences of atrial flutter 3
  • Rate and rhythm control treatment, with the choice of treatment depending on the specific patient population and underlying substrate 4, 5

Nonpharmacological Methods

Nonpharmacological methods, such as radiofrequency catheter ablation, provide new treatment options in the management of patients with drug-resistant or hemodynamically unstable atrial flutter 6, 3

Anticoagulation Therapy

Anticoagulation therapy may be necessary to prevent thromboembolic complications, although the risk is less than that for atrial fibrillation 2, 6, 3

Patient-Specific Treatment

The optimal treatment for atrial flutter may vary depending on the specific patient population, such as those with heart failure, cardiomyopathies, or respiratory disorders 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management of atrial flutter.

Cardiology in review, 2001

Research

Atrial Flutter in Particular Patient Populations.

Cardiac electrophysiology clinics, 2022

Research

Atrial flutter--update on the mechanism and treatment.

Pacing and clinical electrophysiology : PACE, 1992

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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