What is the likely diagnosis for a 24-year-old male-to-female transgender patient with a history of self-harm by slamming their wrist/arm on a desk, now experiencing wrist pain and a 'clicky noise' when using a computer mouse for extended periods?

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Differential Diagnosis for Wrist Pain with "Clicky Noise"

  • Single most likely diagnosis:
    • De Quervain's tenosynovitis: This condition is characterized by inflammation of the tendons on the thumb side of the wrist, which can cause pain and a "clicking" or "snapping" sensation when moving the wrist or thumb. The patient's history of repetitive wrist motion while using a mouse and the presence of a "clicky noise" support this diagnosis.
  • Other Likely diagnoses:
    • Repetitive strain injury (RSI): The patient's recent increase in wrist pain with prolonged mouse use suggests an RSI, which can cause pain, stiffness, and swelling in the affected area.
    • Ganglion cyst: A ganglion cyst is a non-cancerous lump that can develop on the wrist, causing pain, stiffness, and a "clicking" sensation.
    • Wrist sprain or strain: The patient's history of self-harm by slamming their wrist/arm on a desk may have caused a sprain or strain, leading to ongoing pain and stiffness.
  • Do Not Miss diagnoses:
    • Fracture or osteonecrosis: Although less likely, it is essential to rule out a fracture or osteonecrosis, particularly given the patient's history of self-harm, as these conditions can have severe consequences if left untreated.
    • Nerve compression or neuropathy: Conditions like carpal tunnel syndrome or radial nerve compression can cause wrist pain, numbness, and tingling, and can have significant consequences if not addressed.
  • Rare diagnoses:
    • Rheumatoid arthritis or other autoimmune disorders: Although less common, it is possible that the patient's wrist pain is related to an underlying autoimmune disorder, which would require further evaluation and treatment.
    • Tendinous or ligamentous rupture: A rupture of a tendon or ligament in the wrist can cause severe pain and instability, and may require surgical intervention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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