What is the differential diagnosis for generalized dermatitis covering almost the entire body?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Dermatitis Almost All Over the Body

Single Most Likely Diagnosis

  • Atopic Dermatitis (Eczema): This is the most common type of dermatitis and can cover large areas of the body. It's characterized by itchy, inflamed skin and is often associated with allergies and asthma.

Other Likely Diagnoses

  • Contact Dermatitis: This condition occurs when the skin comes into contact with an allergen or irritant, causing a reaction. It can be widespread if the individual is exposed to the allergen or irritant over a large area of their body.
  • Seborrheic Dermatitis: While typically affecting the scalp, face, and torso, in severe cases, seborrheic dermatitis can spread to other areas, causing widespread dermatitis.
  • Psoriasis: An autoimmune condition that speeds up the life cycle of skin cells, causing cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that itch or burn.

Do Not Miss Diagnoses

  • Staphylococcal Scalded Skin Syndrome (SSSS): A serious condition caused by staphylococcal toxins that typically affects infants and young children, but can occur in adults with significant comorbidities. It presents with widespread skin exfoliation and can be life-threatening if not promptly treated.
  • Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS): These are severe skin conditions usually triggered by medications. They can cause widespread skin necrosis and detachment, and are medical emergencies.
  • Pemphigus Vulgaris: An autoimmune disease that causes blistering of the skin and mucous membranes. It can be life-threatening if not treated properly.

Rare Diagnoses

  • Pityriasis Rubra Pilaris (PRP): A rare skin disorder characterized by constant inflammation and scaling (exfoliation) of the skin. It can cover large areas of the body and has several subtypes.
  • Erythroderma (Exfoliative Dermatitis): A condition characterized by widespread scaling, redness, and peeling of the skin, often involving more than 90% of the body surface. It can be a manifestation of underlying conditions such as psoriasis, eczema, or lymphoma.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.