What are the causes of hypertension (high blood pressure) and what is the indication for a computed tomography (CT) scan of the brain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Hypertension is primarily caused by a combination of genetic factors, lifestyle choices, and certain medical conditions, and a CT scan of the brain is crucial in detecting complications such as stroke, bleeding, or brain swelling, especially in cases of severe or sudden hypertension, as recommended by the 2020 international society of hypertension global hypertension practice guidelines 1.

Causes of High Hypertension

The causes of high hypertension include:

  • Genetic factors
  • Lifestyle choices, such as obesity, high sodium intake, physical inactivity, excessive alcohol consumption, stress, and smoking
  • Certain medical conditions, such as kidney disease, thyroid disorders, and sleep apnea

Importance of CT Scan for Brain

A CT scan of the brain is essential in detecting complications related to high hypertension, including:

  • Stroke
  • Bleeding
  • Brain swelling This imaging is particularly important if a patient experiences neurological symptoms like severe headaches, confusion, vision changes, or weakness, which might indicate hypertensive emergency affecting the brain, as stated in the esc council on hypertension position document on the management of hypertensive emergencies 1.

Guidelines for Hypertension Management

The current recommendations for hypertension management are to treat to <140/90 mmHg or <130/80 mmHg in patients with diabetes mellitus or chronic kidney disease, as indicated in the 2015 american heart association scientific statement on congenital heart disease in the older adult 1.

Diagnostic Workup

The standard diagnostic workup of hypertension includes assessment of target organ damage and exclusion of identifiable causes of hypertension, such as sleep apnea, nonsteroidal anti-inflammatory drug use, chronic kidney disease, endocrine causes, renovascular disease, and coarctation, as recommended in the 2020 international society of hypertension global hypertension practice guidelines 1.

From the Research

Causes of High Hypertension

  • High hypertension can be caused by various factors, including lifestyle habits and underlying medical conditions 2, 3.
  • Some of the lifestyle factors that contribute to high hypertension include a high-sodium diet, low potassium intake, physical inactivity, and excessive alcohol consumption 2, 3.
  • Certain medical conditions, such as kidney disease, can also increase the risk of developing high hypertension 4.

Importance of Controlling Hypertension

  • Controlling hypertension is crucial to reduce the risk of cardiovascular disease, stroke, and kidney disease 2, 3, 5.
  • Studies have shown that reducing blood pressure can decrease the risk of cardiovascular events by approximately 20-30% 2.
  • The American Heart Association recommends lifestyle modifications, such as weight loss, healthy dietary patterns, and regular exercise, as the first line of treatment for hypertension 2, 3.

Use of CT Scan for Brain

  • A CT scan may be ordered to evaluate the brain in patients with high hypertension, especially if there are concerns about hemorrhagic stroke or other cerebrovascular complications 5.
  • The scan can help identify any abnormalities in the brain, such as bleeding or damage to blood vessels, which may be related to high hypertension 5.
  • In some cases, a CT scan may be used to monitor the effects of treatment on the brain and to adjust the treatment plan as needed 5.

Treatment of Hypertension

  • The treatment of hypertension typically involves a combination of lifestyle modifications and medication 2, 3, 6, 4.
  • First-line medications for hypertension include thiazide diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and calcium channel blockers 2, 3, 6, 4.
  • The choice of medication depends on various factors, including the patient's medical history, kidney function, and other health conditions 6, 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.