What should be done for a patient with gasoline exposure to the eyes?

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Last updated: January 24, 2026View editorial policy

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Gasoline Eye Exposure: Immediate Management

Immediately irrigate the eyes with copious amounts of tap water for at least 15 minutes, starting at the scene of exposure without any delay. 1, 2, 3

Immediate Decontamination Protocol

Begin irrigation immediately at the scene—every second of delay increases the risk of permanent ocular damage from hydrocarbon exposure. 2, 3, 4

Primary Irrigation Technique

  • Use tap water as the first-line irrigation fluid because it is readily available, safe, and effective for chemical eye exposures. 1, 2, 3, 4
  • Continue irrigation for a minimum of 15 minutes, though some severe chemical exposures may require up to 30 minutes or even 2 hours of continuous irrigation. 1, 2, 4
  • Direct the irrigation flow away from the unaffected eye to prevent cross-contamination and conversion of a unilateral injury to bilateral. 2, 3
  • Assist the patient in keeping eyelids open during irrigation as many patients will require help maintaining adequate exposure of the ocular surface. 2, 3

Alternative Irrigation Solutions

  • If immediately available at the scene, normal saline, Ringer's lactate solution, or commercial eye wash solutions are reasonable alternatives to tap water. 1, 2, 3
  • Never delay irrigation to search for "better" solutions—immediate decontamination with whatever water is available takes absolute priority over finding specialized irrigation fluids. 2, 3

Critical Pitfalls to Avoid

Do not delay irrigation to transport the patient or search for specialized equipment—begin flushing immediately with whatever water source is available. 2, 3

Avoid contaminating the unaffected eye, other individuals, or surrounding areas during the irrigation process, as gasoline can cause injury to anyone exposed. 1, 2, 3

When to Stop Irrigation

Continue irrigation until a healthcare professional can evaluate the injury and confirm that the pH of the eye has returned to normal (physiologic pH of approximately 7.0-7.4). 2, 3

Post-Irrigation Management

Immediate Medical Evaluation

  • Contact emergency medical services (EMS) or transport to an emergency department for formal ophthalmologic assessment after initial irrigation is complete. 1
  • Contact regional poison control centers for expert guidance on management of severe hydrocarbon eye exposures. 1, 2

Supportive Ocular Care

  • Apply nonpreserved lubricant eye drops (hyaluronate or carmellose) every 2 hours if significant irritation persists after irrigation. 2
  • Arrange urgent ophthalmology consultation to assess for corneal epithelial damage, conjunctival injury, and potential long-term complications. 2

Infection Prophylaxis

  • Initiate broad-spectrum topical antibiotic prophylaxis (such as moxifloxacin four times daily) if corneal fluorescein staining or epithelial defects are present on examination. 2

Anti-inflammatory Treatment

  • Consider topical corticosteroid drops (dexamethasone 0.1%) only under direct ophthalmologic supervision to reduce ocular surface inflammation, but use with extreme caution as corticosteroids can mask signs of corneal infection. 2

Systemic Complications to Monitor

Be aware that gasoline absorption through ocular tissues can cause systemic toxicity, including pulmonary, cardiovascular, neurologic, renal, and hepatic complications, particularly with gasolines containing lead additives. 5

Monitor for signs of systemic hydrocarbon toxicity including respiratory distress, cardiac arrhythmias, altered mental status, and renal dysfunction. 5

Follow-Up Requirements

  • Daily ophthalmologic review is mandatory during the acute phase (typically 7-14 days) to assess healing progress and adjust treatment. 2
  • Continue lubricant eye drops every 2 hours throughout the acute illness phase until complete epithelial healing occurs. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment for Eye Exposure to Chemical Substances

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Eye Irritation After Chemical Exposure

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Caustic injuries of the eye, skin and the gastrointestinal tract].

Therapeutische Umschau. Revue therapeutique, 2009

Research

Hydrocarbon contact injuries.

The Journal of trauma, 1985

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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