When to Perform an EKG on Patients with Potential Heart Symptoms
An EKG must be obtained and interpreted within 10 minutes of arrival for any patient presenting with chest pain or symptoms suggestive of acute coronary syndrome (ACS), regardless of setting. 1
Immediate EKG Indications (Within 10 Minutes)
Acute Presentations Requiring Emergency EKG
Any chest pain or anginal equivalent symptoms (dyspnea, jaw pain, arm pain, epigastric discomfort) warrant immediate 12-lead EKG acquisition and interpretation by an experienced physician within 10 minutes 1
Suspected acute coronary syndrome based on clinical presentation requires immediate EKG, with the tracing shown to an experienced emergency physician as soon as possible after ED arrival 1
Palpitations, syncope, or near-syncope in patients with potential cardiac etiology require immediate EKG evaluation 1
New or worsening dyspnea that could represent cardiac origin necessitates prompt EKG 1
Serial EKG Protocol for Non-Diagnostic Initial Tracings
If the initial EKG is non-diagnostic but symptoms persist or clinical suspicion for ACS remains high, obtain serial EKGs at 15-30 minute intervals to detect evolving ST-segment changes 1
Repeat EKG immediately if symptoms recur, change in character, or clinical condition deteriorates 1
Continue monitoring until ACS is ruled out with cardiac biomarkers and clinical assessment 1
Office/Outpatient Setting EKG Indications
Stable Chest Pain Evaluation
All patients presenting with stable chest pain in the office setting should receive an EKG; if unavailable, immediate transfer to ED is required 1
If EKG cannot be obtained in the office, do not delay—transfer the patient to the ED by EMS immediately rather than attempting further evaluation 1
High-Risk Symptoms Requiring EKG
Unexplained change in usual anginal pattern warrants repeat EKG even in known cardiac patients 1
Extreme fatigue, weakness, or prostration of unclear etiology should prompt EKG evaluation 1
New-onset exertional symptoms in patients with cardiac risk factors require EKG assessment 2, 3
Supplemental EKG Leads for Specific Scenarios
Posterior wall MI evaluation: Obtain leads V7-V9 when initial EKG is non-diagnostic but intermediate-to-high clinical suspicion for ACS persists, particularly if inferior wall changes are present 1
Right ventricular involvement: Consider right-sided leads (V3R, V4R) when ongoing ischemia is suspected and standard leads are inconclusive 1
Continuous Cardiac Monitoring Indications
Acute Coronary Syndromes
Begin continuous rhythm monitoring immediately upon presentation and continue until NSTEMI is established or ruled out 1
Minimum 24 hours of monitoring for uncomplicated acute MI, starting from ED presentation and continuing uninterrupted including during intra-hospital transport 1
Extended monitoring beyond 24 hours is required for complicated MI cases with ongoing ischemia, heart failure, cardiogenic shock, or arrhythmias requiring intervention 1
Continue monitoring 24 hours after complications resolve in patients with recurrent ischemia or hemodynamic instability 1
Post-Cardiac Surgery
48-72 hours minimum monitoring after uncomplicated cardiac surgery 1
Monitor until hospital discharge for high-risk patients (advanced age, history of atrial fibrillation, valvular disease, preoperative β-blocker withdrawal) due to peak atrial fibrillation risk on postoperative days 2-4 1
Other Critical Indications
Acute heart failure/pulmonary edema: Continue monitoring until signs and symptoms resolve and no hemodynamically significant arrhythmias for 24 hours 1
Hemodynamically unstable arrhythmias: Monitor continuously until stability achieved 1
Procedures requiring conscious sedation: Monitor throughout procedure and until patient is awake, alert, and hemodynamically stable 1
Pre-Treatment EKG Requirements for Specific Medications
Baseline EKG Mandatory Before Initiating
Tricyclic antidepressants (e.g., nortriptyline): Obtain baseline EKG before starting, repeat at steady state (1-2 weeks), and after any dose changes; QRS widening >50% or QTc >500 msec requires dose reduction or discontinuation 4
Lacosamide: Obtain baseline EKG in patients with cardiac history (syncope, structural heart disease) or those on PR-prolonging medications (beta-blockers, calcium channel blockers, digoxin) 5
Risk-Based EKG Screening
- ADHD medications: The American Academy of Pediatrics recommends thorough cardiac history and physical examination for all patients, reserving EKG only for those with identified cardiac risk factors (personal history of syncope, chest pain, palpitations, exercise intolerance; family history of sudden death <50 years, inherited arrhythmia syndromes) 6
Common Pitfalls to Avoid
Never delay transfer for troponin measurement if EKG cannot be obtained in office setting—this causes detrimental delays in care 1
Do not assume normal initial EKG excludes ACS—approximately 1.3% of patients with normal EKGs can still have MI, requiring serial EKGs and troponin measurements 7
Failing to obtain baseline EKG before cardiotoxic medications makes it impossible to detect drug-induced changes and represents a critical patient safety error 4
Women experience significant delays in time-to-EKG (mean 53 minutes vs 34 minutes for men); actively work to eliminate this disparity 8
Comparison with prior EKGs is essential—always obtain and review previous tracings when available to detect subtle changes 1, 2