What is the cause of bilateral flank pain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Bilateral Flank Pain

Single Most Likely Diagnosis

  • Nephrolithiasis (Kidney Stones): This condition is a common cause of bilateral flank pain, especially if the stones are moving or obstructing the ureters. The pain is often severe and can radiate to the groin.

Other Likely Diagnoses

  • Pyelonephritis: An infection of the kidneys that can cause bilateral flank pain, fever, and other urinary symptoms.
  • Glomerulonephritis: Inflammation of the glomeruli in the kidneys, which can cause flank pain, hematuria, and proteinuria.
  • Polycystic Kidney Disease (PKD): A genetic disorder characterized by the growth of numerous cysts in the kidneys, which can cause bilateral flank pain, hematuria, and kidney failure.

Do Not Miss Diagnoses

  • Abdominal Aortic Aneurysm: A potentially life-threatening condition that can cause bilateral flank pain, especially if the aneurysm is rupturing.
  • Sickle Cell Crisis: A condition that can cause severe pain, including bilateral flank pain, due to vaso-occlusion in the kidneys.
  • Renal Vein Thrombosis: A blood clot in the renal veins that can cause bilateral flank pain, hematuria, and kidney failure.

Rare Diagnoses

  • Alport Syndrome: A rare genetic disorder that affects the type IV collagen in the kidneys, ears, and eyes, causing bilateral flank pain, hematuria, and kidney failure.
  • Amyloidosis: A condition characterized by the deposition of abnormal proteins in the kidneys, which can cause bilateral flank pain, proteinuria, and kidney failure.
  • Renal Artery Stenosis: Narrowing of the renal arteries that can cause bilateral flank pain, hypertension, and kidney failure.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.