What error did the physician make in diagnosing a patient with chest pain and shortness of breath (SOB) who was prescribed a proton pump inhibitor (PPI) for suspected acid reflux, but was later found to have congestive heart failure (CHF) after their condition worsened?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 25, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Cognitive Bias: Premature Closure

The physician made the error of premature closure—accepting the first plausible diagnosis (acid reflux) without adequately considering or ruling out life-threatening alternatives like congestive heart failure when the patient presented with chest pain and shortness of breath.

Understanding the Error

This case exemplifies a classic diagnostic error pattern where the physician:

  • Rapidly processed the patient's presentation and locked onto a single diagnosis (acid reflux) without broadening the differential diagnosis 1, 2
  • Failed to recognize that chest pain and shortness of breath are cardinal symptoms requiring cardiac evaluation first, regardless of whether GERD seems plausible 3
  • Committed premature closure of the diagnostic process, which is one of the most common causes of diagnostic errors reported by family physicians 2

The correct answer is B - First impression of the patient (premature closure based on initial impression).

Why This Error Occurred

Cognitive Factors

  • Premature closure is the tendency to accept the first diagnosis that fits and stop considering alternatives 1, 2
  • Physicians commonly fail to "look beyond the initial, most obvious diagnosis," which was identified as a key lesson learned from diagnostic errors 1
  • Atypical presentations of serious disease (like CHF presenting as "acid reflux") are frequently missed 1

The Critical Missed Step

  • Any patient with new chest pain requires cardiac evaluation first, regardless of how convincing the GERD presentation appears 3
  • Approximately 30% of non-cardiac chest pain is caused by GERD, meaning 70% have other causes including cardiac disease 3
  • The physician should have considered that "any discomfort above the umbilicus may be coronary artery disease" or cardiac pathology 1

What Should Have Been Done

Immediate Assessment Required

  • Rule out cardiac causes through appropriate evaluation (ECG, cardiac biomarkers, clinical assessment for heart failure) before attributing symptoms to GERD 3
  • Recognize that chest pain + shortness of breath is a high-risk presentation requiring urgent evaluation 4, 3
  • If chest pain is unimproved or worsening after 5 minutes, emergency evaluation is mandatory 3

Proper Diagnostic Approach

  • Broaden the differential diagnosis to include CHF, acute coronary syndrome, pulmonary embolism, and other life-threatening conditions 1, 2
  • Only after excluding dangerous causes should a PPI trial be considered 4
  • For patients with atypical symptoms (chest pain without classic heartburn), consider objective testing before empiric PPI therapy rather than assuming GERD 4

Common Pitfalls to Avoid

  • Never assume chest pain is benign or GERD-related without cardiac evaluation, even when the presentation seems to fit acid reflux 3
  • Avoid anchoring on the first diagnosis that comes to mind—this is the essence of premature closure 1, 2
  • Be alert to atypical presentations of serious disease—CHF can present with symptoms mimicking GERD 1
  • Hurry and distraction are the most common physician stressors leading to diagnostic errors 2

The Lesson

The physician's error was cognitive bias (premature closure), not simply being rushed (option A) or poor communication (option C). While those factors may have contributed, the fundamental problem was accepting the first impression without considering life-threatening alternatives 1, 2. This represents a failure in the diagnostic reasoning process where the physician stopped thinking too soon 5, 2.

References

Research

Diagnostic errors in primary care: lessons learned.

Journal of the American Board of Family Medicine : JABFM, 2012

Research

Perceived causes of family physicians' errors.

The Journal of family practice, 1995

Guideline

Management of Chest Pain and Acid Reflux After Starting Fluoxetine

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Diagnosing diagnostic error.

Current problems in pediatric and adolescent health care, 2013

Related Questions

What are the treatment options for refractory Gastroesophageal Reflux Disease (GERD)?
What is the best management for coughing due to Gastroesophageal Reflux Disease (GERD) that persists despite Proton Pump Inhibitor (PPI) use?
What is the best medication for chronic epigastric pain?
What is the best medication for gastric hyperactivity (gastroesophageal reflux disease)?
What is the best next step for a patient with a history of Gastroesophageal Reflux Disease (GERD) on maximum dose of Proton Pump Inhibitor (PPI) with mild improvement and a normal endoscopy?
What is the best approach to manage perianal dermatitis in young children?
What is the initial management and evaluation for an adult patient with no significant medical history and elevated globulin levels?
Is Sinupret (herbal supplement) effective for treating allergies in patients with allergic rhinitis?
What is the diagnosis and treatment for a 10-month-old infant with a 3-day history of rhinorrhea, fever, irritability, and decreased appetite, who also has a bulging and erythematous tympanic membrane with effusion in the right ear, lymphadenopathy, and is presenting with tachycardia, tachypnea, and hyperthermia?
What are the post-implantation instructions and precautions for a patient after In Vitro Fertilization (IVF) implantation?
What are the immediate steps for a female patient of reproductive age with urgent Polycystic Ovary Syndrome (PCOS) symptoms, including severe pelvic pain, heavy bleeding, or signs of ovarian torsion?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.