What is the diagnosis and management for a 31-year-old female with a 2-day history of fever, white nasal discharge, intermittent headache, thick green phlegm, and sore throat, who has been taking Paracetamol (acetaminophen) 500 mg every 4 hours, with physical examination findings of swollen non-erythematous turbinates?

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Diagnosis and Management

Most Likely Diagnosis

This patient has acute viral nasopharyngitis (common cold) that is resolving appropriately, with no indication for antibiotics at this time. 1

The clinical presentation—2 days of fever, white nasal discharge transitioning to thick green phlegm, headache, sore throat, and swollen non-erythematous turbinates—is classic for viral upper respiratory infection. 1 Importantly, symptoms have already improved significantly after only 2 days, with fever and most symptoms resolved except productive cough. 1

Why This Is NOT Bacterial Sinusitis

Patients with symptoms for fewer than 7 days are unlikely to have bacterial infection and do not require antibiotics. 1 The key diagnostic criteria for acute bacterial rhinosinusitis (ABRS) require:

  • Duration ≥10 days without improvement, OR 2, 3
  • Severe symptoms (high fever ≥39°C with purulent discharge for ≥3-4 consecutive days), OR 1
  • "Double worsening" (initial improvement followed by worsening within 10 days) 2, 3

This patient meets none of these criteria—she is only on day 2 and already improving. 1

Critical Point About Green/Purulent Discharge

Do not prescribe antibiotics based on purulent nasal discharge alone—this is a normal feature of viral colds. 1 Secretions naturally become thicker and colored (yellow-green) after a few days in viral infections, then clear before resolution. 2 This color change reflects neutrophil activity, not bacterial infection. 2

Recommended Management

Continue Symptomatic Treatment Only

No antibiotics are indicated. 1 The patient should continue:

  • Acetaminophen or NSAIDs (ibuprofen) for any residual discomfort or fever 1

    • Current dosing of 500 mg paracetamol every 4 hours is appropriate 4
  • Nasal saline irrigation to facilitate clearance of nasal secretions and provide modest symptom relief 1

  • Short-term nasal decongestant (oxymetazoline) if severe nasal congestion develops, but strictly limit to 3 days maximum to avoid rhinitis medicamentosa 3

What NOT to Do

Avoid antihistamines—the presence of rhinorrhea and cough strongly suggests viral etiology, and antihistamines provide no benefit in non-allergic viral infections while potentially worsening congestion by thickening secretions. 3

Do not order imaging (CT or plain radiography)—diagnosis is clinical and imaging is not indicated for uncomplicated cases. 3

When to Reassess

Instruct the patient to return if:

  • Symptoms persist ≥10 days without improvement 1, 3
  • High fever ≥39°C with purulent nasal discharge or facial pain for ≥3-4 consecutive days 1
  • Worsening symptoms after initial improvement (double worsening pattern) 1, 3

Any of these would indicate possible progression to ABRS and warrant consideration of antibiotics (amoxicillin as first-line). 3

Patient Education

Reassure the patient that:

  • Symptoms typically last up to 2 weeks and are self-limited 1
  • The illness resolves without antibiotics, even when bacterial pathogens are present 1
  • Persistent productive cough for several days after other symptoms resolve is normal and expected 1
  • Hand hygiene is the most effective method to reduce transmission 1

Physical Examination Findings Explained

Swollen non-erythematous turbinates are consistent with viral rhinitis. 2 Red, swollen nasal tissue would suggest infectious rhinitis/sinusitis, while pale boggy turbinates suggest allergic rhinitis—neither applies here. 2 The non-erythematous swelling supports viral inflammation without bacterial superinfection. 2

References

Guideline

Management of Acute Nasopharyngitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment for Persistent Nasal Congestion and Cough at 10 Days

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Paracetamol efficacy and safety in children: the first 40 years.

American journal of therapeutics, 2000

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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