What is the cause of a blind spot in the center of vision in both eyes?

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Last updated: April 16, 2025View editorial policy

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Differential Diagnosis for Blank Space in Center of Vision Both Eyes

  • Single Most Likely Diagnosis
    • Macular Degeneration: This condition is a leading cause of vision loss in older adults, characterized by the deterioration of the macula, which is responsible for central vision. The symptoms can include a blank or blurry spot in the center of the visual field, affecting one or both eyes.
  • Other Likely Diagnoses
    • Diabetic Macular Edema: A complication of diabetes that results in fluid accumulation in the macula, leading to distorted and blurred vision, which can manifest as a blank space in the center of vision.
    • Macular Hole: A small break in the macula that can cause blurred and distorted vision, with patients often describing a blank or missing area in their central visual field.
    • Central Serous Chorioretinopathy (CSC): A condition where fluid accumulates under the retina, causing a detachment and leading to a blind spot or blurred vision in the center of the visual field.
  • Do Not Miss Diagnoses
    • Optic Neuritis: Inflammation of the optic nerve that can cause pain and vision loss, including a central scotoma (blind spot). Although less common, missing this diagnosis could lead to delayed treatment and potential permanent vision loss.
    • Pituitary Tumor: Although rare, a tumor in the pituitary gland can compress the optic chiasm, leading to bitemporal hemianopia or, less commonly, central visual field defects if the tumor affects the optic nerves directly.
  • Rare Diagnoses
    • Leber's Hereditary Optic Neuropathy (LHON): A rare inherited disease that causes central vision loss, typically in young adults. It's characterized by a sudden, painless loss of vision, often starting in one eye and then affecting the other.
    • Toxic or Nutritional Optic Neuropathy: Certain toxins or nutritional deficiencies can cause optic nerve damage, leading to central vision loss. Examples include methanol poisoning or deficiencies in vitamin B12.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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