What is the cause of right-sided chest pain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025 • View editorial policy

Differential Diagnosis for Right Sided Chest Pain

Single Most Likely Diagnosis

  • Musculoskeletal strain: This is often the most common cause of right-sided chest pain, resulting from overuse or injury to the muscles and bones in the chest wall. The pain is typically sharp and worsens with movement or deep breathing.

Other Likely Diagnoses

  • Pneumonia: Infection of the lung can cause chest pain, which may be localized to one side. The pain is often accompanied by fever, cough, and difficulty breathing.
  • Pulmonary embolism: A blood clot in the lungs can cause sudden, severe chest pain that may be worse on one side. Other symptoms include shortness of breath, cough, and leg swelling.
  • Gastroesophageal reflux disease (GERD): Stomach acid flowing up into the esophagus can cause chest pain, which may be felt on one side. The pain is often accompanied by heartburn and worsens with eating or lying down.
  • Costochondritis: Inflammation of the cartilage that connects the ribs to the breastbone can cause sharp chest pain, which may be localized to one side.

Do Not Miss Diagnoses

  • Myocardial infarction (heart attack): Although less common on the right side, a heart attack can cause chest pain that may be localized to one area. It is crucial to consider this diagnosis, especially in patients with risk factors.
  • Aortic dissection: A tear in the aorta can cause severe, sudden chest pain that may be worse on one side. This is a medical emergency that requires immediate attention.
  • Pneumothorax: A collapsed lung can cause sudden, severe chest pain that may be worse on one side. Other symptoms include shortness of breath and decreased breath sounds on the affected side.

Rare Diagnoses

  • Lung cancer: A tumor in the lung can cause chest pain, which may be localized to one side. Other symptoms include cough, weight loss, and difficulty breathing.
  • Tuberculosis: A bacterial infection of the lung can cause chest pain, which may be localized to one side. Other symptoms include cough, fever, and weight loss.
  • Sickle cell disease: A genetic disorder that affects the blood can cause chest pain, which may be localized to one side. Other symptoms include anemia, jaundice, and episodes of pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.