What is the recommended dose of Bromfed (Brompheniramine and Pseudoephedrine) for a pediatric patient weighing 63 pounds?

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Bromfed Dosing for a 63-Pound Patient

I cannot provide a specific dose recommendation for Bromfed (brompheniramine/pseudoephedrine) in this patient because none of the provided evidence addresses this medication or its components.

Critical Gap in Evidence

The evidence provided contains guidelines for:

  • Tuberculosis treatment 1
  • Anaphylaxis management 1
  • Pediatric advanced life support 1
  • Influenza chemoprophylaxis 1
  • Venous thromboembolism treatment 1
  • Multidrug-resistant tuberculosis 1
  • Epinephrine autoinjectors 1
  • Various pediatric emergency medications 1
  • Other unrelated medications 2, 3, 4

None of these sources provide dosing information for brompheniramine or pseudoephedrine, the active ingredients in Bromfed.

General Pediatric Dosing Principles

While I cannot provide the specific Bromfed dose, the evidence does establish important principles:

Weight Conversion

  • 63 pounds = approximately 28.6 kg (this conversion is essential for any weight-based dosing calculation)

Dosing Considerations

  • Pediatric doses cannot be simply scaled down from adult doses using weight alone, as this results in doses that are too small in children because elimination does not change in direct proportion to weight 5
  • Patient weight in kilograms should be included on all medication prescriptions to allow proper dose verification 6
  • Published pediatric dosing rules (such as Clark's weight rule or Young's age rule) have been shown to differ significantly from actual appropriate doses and are unreliable 7

Required Action

To obtain the correct Bromfed dose for this 28.6 kg patient, you must consult:

  • The FDA-approved product labeling for Bromfed
  • A current pediatric drug reference (e.g., Lexicomp, Micromedex)
  • A pediatric pharmacist or clinical pharmacology resource

The dose will depend on the specific formulation of Bromfed being used and whether this patient meets age and weight criteria for safe administration of combination antihistamine/decongestant products.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Guaifenesin Dosing Guidelines for Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Metoclopramide Administration in Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Hydroxyzine Syrup Dosing and Administration in Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Patient Weight Should Be Included on All Medication Prescriptions.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2023

Research

Pediatric dosing--the pharmacist's dilemma.

Contemporary pharmacy practice, 1980

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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