What is the diagnosis and treatment for a 21-year-old female presenting with a painful, enlarged thrombosed external hemorrhoid, with a scant amount of bleeding, after lifting weights, unresponsive to witch hazel, warm soaks, and Preparation H (phenylephrine) cream?

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Differential Diagnosis for a 21-year-old Female with a Hemorrhoid

  • Single most likely diagnosis:
    • Thrombosed external hemorrhoid: This is the most likely diagnosis given the patient's history of lifting weights, which can cause increased intra-abdominal pressure leading to hemorrhoid formation. The description of a firm, pink, and tender hemorrhoid on exam is consistent with a thrombosed external hemorrhoid. The patient's symptoms of pain and a scant amount of blood when wiping also support this diagnosis.
  • Other Likely diagnoses:
    • Non-thrombosed external hemorrhoid: Although less likely than a thrombosed hemorrhoid given the description of the hemorrhoid being firm and tender, a non-thrombosed external hemorrhoid could still present with similar symptoms.
    • Internal hemorrhoid with prolapse: This could be considered if the hemorrhoid is reducible and the patient has a history of straining during bowel movements or other activities that increase intra-abdominal pressure.
  • Do Not Miss diagnoses:
    • Anal fissure: Although the patient denies abdominal pain and fever, an anal fissure could present with pain and bleeding, especially if the fissure is deep or has become infected. It's crucial to rule out this condition due to the potential for severe pain and complications if left untreated.
    • Rectal cancer: Although extremely rare in a 21-year-old, rectal cancer can present with rectal bleeding and pain. Given the potential severity of this diagnosis, it should not be missed, even if it is highly unlikely.
    • Inflammatory bowel disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause rectal bleeding, pain, and other gastrointestinal symptoms. While less likely in this scenario, IBD should be considered, especially if the patient's symptoms do not improve with treatment for a hemorrhoid.
  • Rare diagnoses:
    • Rectal varices: These are dilated veins in the rectum that can cause bleeding. They are less common than hemorrhoids and usually associated with portal hypertension.
    • Rectal ulcers: These can cause pain and bleeding but are less common and might be associated with specific conditions such as solitary rectal ulcer syndrome.
    • Proctitis: Inflammation of the rectum can cause pain, bleeding, and discharge. It can be due to infectious or inflammatory causes and is less likely given the patient's presentation but should be considered if other diagnoses are ruled out.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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