Treatment of Bell's Palsy in Adults
Prescribe oral corticosteroids within 72 hours of symptom onset—specifically prednisolone 50 mg daily for 10 days or prednisone 60 mg daily for 5 days followed by a 5-day taper—as this is the only proven effective treatment that significantly improves facial nerve recovery. 1
Immediate Management (Within 72 Hours)
Corticosteroid Therapy
- Start corticosteroids immediately upon diagnosis for patients 16 years and older, as treatment effectiveness diminishes rapidly after the 72-hour window 1
- The evidence is compelling: 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months versus 81.6% with placebo 1
- Two acceptable regimens exist:
Antiviral Therapy Considerations
- Never prescribe antivirals alone—they are completely ineffective as monotherapy 1, 3
- You may offer combination therapy (corticosteroids plus antivirals) within 72 hours, though the added benefit is minimal 1, 2
- If choosing combination therapy, use valacyclovir 1 g three times daily for 7 days OR acyclovir 400 mg five times daily for 10 days 1, 2
- The decision to add antivirals should acknowledge that while complete recovery rates may increase slightly (96.5% versus 89.7% with steroids alone), the benefit is small and corticosteroids remain the cornerstone 1
Critical Eye Protection Protocol
Immediate Implementation
Implement comprehensive eye protection immediately for all patients with impaired eye closure to prevent permanent corneal damage. 1
Daytime Protection
- Apply lubricating ophthalmic drops every 1-2 hours while awake 1
- Use sunglasses outdoors to protect against wind and foreign particles 1
- Consider moisture chambers using polyethylene covers for severe cases 1
Nighttime Protection
- Apply ophthalmic ointment at bedtime for sustained moisture retention 1
- Use eye taping or patching with careful instruction on proper technique to avoid corneal abrasion 1
- Critical pitfall: Improper taping technique can cause corneal abrasion—demonstrate the technique and have the patient practice 1
Urgent Ophthalmology Referral Triggers
- Severe impairment with complete inability to close the eye 1
- Any signs of corneal exposure or damage (eye pain, vision changes, redness, discharge, foreign body sensation) 1
- Persistent lagophthalmos beyond 3 months 1
Diagnostic Testing: What NOT to Do
- Do not order routine laboratory tests—they are not recommended for typical Bell's palsy 1, 4
- Do not order diagnostic imaging for straightforward presentations 1, 4
- Electrodiagnostic testing (ENoG, EMG) may be offered only for patients with complete facial paralysis, performed 3-14 days post-onset 1
- Testing before 7 days or after 14-21 days provides unreliable prognostic information due to ongoing Wallerian degeneration 1
Mandatory Follow-Up and Referral Triggers
3-Month Reassessment
Refer all patients with incomplete facial recovery at 3 months to a facial nerve specialist or facial plastic surgeon for evaluation of reconstructive options 1, 4
Immediate Reassessment Required For:
- New or worsening neurologic findings at any point (suggests alternative diagnosis like stroke, tumor, or CNS pathology) 1, 4
- Development of ocular symptoms at any point 1, 4
- Progressive weakness beyond 3 weeks (major red flag for alternative diagnosis) 1
Early Follow-Up Schedule
- Initial visit within 72 hours for treatment initiation and eye care education 1
- Follow-up at 1-2 weeks to assess recovery trajectory, reinforce eye protection, and identify early complications 1
- Most patients begin showing recovery within 2-3 weeks 1, 4
Red Flags Requiring Imaging
Order MRI with and without contrast if any of these features are present 1, 5:
- Recurrent paralysis on the same side 1
- Isolated branch paralysis (not diffuse facial nerve involvement) 1, 5
- Other cranial nerve involvement 1, 5
- Bilateral facial weakness 5, 4
- No recovery after 3 months 1, 5
- Progressive weakness beyond expected timeline 1
Therapies to AVOID
Not Recommended
- Physical therapy: No proven benefit over spontaneous recovery 1, 3
- Acupuncture: Poor-quality trials with indeterminate benefit-harm ratio 1
- Surgical decompression: Rarely indicated except in specialized circumstances 1
Prognosis Counseling
Expected Recovery Rates
- Patients with incomplete paralysis: up to 94% complete recovery 1, 4
- Patients with complete paralysis: approximately 70% complete recovery within 6 months 1, 4
- Most patients begin recovery within 2-3 weeks, with complete recovery typically by 3-4 months 1, 4
Long-Term Complications
- Approximately 30% may experience permanent facial weakness with muscle contractures 1, 4
- Potential complications include lacrimal dysfunction, nasal airway obstruction, oral incompetence, and significant psychosocial impact 1
- Screen for depression in patients with persistent paralysis and refer when needed 1
Common Clinical Pitfalls
- Delaying corticosteroids beyond 72 hours: Treatment effectiveness drops significantly 1
- Prescribing antivirals alone: Completely ineffective and delays appropriate treatment 1, 3
- Inadequate eye protection monitoring: Can lead to permanent corneal damage 1
- Failing to refer at 3 months: Delays access to reconstructive options and psychological support 1
- Missing atypical features: Bilateral weakness, isolated branch paralysis, or other cranial nerve involvement suggest alternative diagnoses requiring different management 1, 5
- Underdosing steroids: Using a standard methylprednisolone dose pack provides only 105 mg prednisone equivalent versus 540 mg over 14 days with proper dosing 1