What is the interpretation of this echocardiogram showing a left ventricular ejection fraction of 60-65%, mitral annular calcification, trace mitral valve regurgitation, and aortic atherosclerosis, and what are the recommended management and treatment options for this patient?

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Echocardiogram Interpretation: Essentially Normal Heart Function

Your echocardiogram shows a healthy, normally functioning heart with only minor age-related changes that require no treatment. 1

What the Key Findings Mean

Heart Pumping Function (Ejection Fraction 60-65%)

  • Your heart is pumping normally. The ejection fraction of 60-65% falls within the normal range (normal is >54% for men, >57% for women). 1
  • This means your heart muscle is contracting effectively and delivering adequate blood flow to your body. 1
  • All four chambers of your heart (left ventricle, right ventricle, left atrium, right atrium) are normal in size and function. 1

Valve Findings: Trace Regurgitation

  • "Trace" regurgitation in three valves (mitral, tricuspid, aortic) is clinically insignificant. These represent trivial leakage that is so minimal it cannot even be detected by physical examination and is commonly found in healthy individuals. 1, 2
  • The American Heart Association confirms that Doppler echocardiography detects physiologic regurgitation that exists on a continuum with pathologic regurgitation, and trace regurgitation requires no intervention or follow-up. 2
  • Your valves are structurally normal with no stenosis (narrowing) or significant dysfunction. 1

Mitral Annular Calcification

  • This represents age-related calcium deposits around the mitral valve ring. It is extremely common in adults and does not affect valve function in your case. 1
  • The calcification is not causing any obstruction or significant regurgitation (you only have trace mitral regurgitation). 1
  • While mitral annular calcification can be associated with cardiovascular risk factors, it serves primarily as a marker rather than a direct cause of problems. 3

Aortic Atherosclerosis

  • This indicates calcium/plaque buildup in your aorta (the main artery leaving your heart). This is a common age-related finding. 4
  • Aortic atherosclerosis should be considered a marker of potential coronary artery disease risk, warranting aggressive management of cardiovascular risk factors. 4
  • Management focuses on controlling modifiable risk factors: blood pressure control, LDL cholesterol lowering with statins, diabetes management if present, smoking cessation, and regular exercise. 4

Clinical Significance and Management

No Intervention Needed for Valve Findings

  • The trace valve regurgitation and mitral annular calcification require no specific treatment. 1, 2
  • These findings do not limit your activities or require medication specifically for the valves. 1
  • The normal chamber sizes confirm that even the trace regurgitation is not causing any hemodynamic consequences. 1

Cardiovascular Risk Factor Management

Your management should focus on preventing progression of atherosclerosis: 4

  • Statin therapy to lower LDL cholesterol (HMG-CoA reductase inhibitors have been shown to decrease progression of aortic valve calcification and atherosclerosis). 4
  • Blood pressure control to target <130/80 mmHg. 4
  • Diabetes management if applicable (maintain HbA1c <7%). 4
  • Smoking cessation if applicable. 4
  • Regular aerobic exercise and heart-healthy diet. 4

Follow-Up Recommendations

  • No specific echocardiographic follow-up is needed for the trace valve regurgitation. 1, 2
  • Routine cardiovascular care with your primary physician or cardiologist focusing on atherosclerosis risk factor modification. 4
  • Repeat echocardiography only if you develop new cardiac symptoms (shortness of breath, chest pain, palpitations, leg swelling). 1

Bottom Line

You have a structurally and functionally normal heart. The trace valve leakage is physiologic and meaningless. The mitral annular calcification and aortic atherosclerosis are age-related findings that signal the importance of aggressive cardiovascular risk factor management—particularly cholesterol control with statins—but do not require valve intervention or restrict your activities. 4, 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Detection and Diagnosis of Mitral Regurgitation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Mitral annular calcification is associated with reduced left ventricular function and inflammation in patients with chronic kidney disease.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2008

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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