Management of Tingling in Hands and Fingers 7 Weeks Post-CABG with Bilateral Internal Mammary Artery Grafts
This presentation is most consistent with brachial plexus injury (neurapraxia) from surgical positioning and sternal retraction during bilateral IMA harvesting, which typically resolves spontaneously within 3-6 months. 1
Primary Etiology: Brachial Plexus Injury from Surgical Positioning
Bilateral internal mammary artery harvesting requires extensive sternal retraction and arm positioning that stretches the brachial plexus, particularly affecting the lower trunk (C8-T1) which supplies sensation to the ulnar aspect of the hand and fingers. 1 The risk of sternal complications is significantly increased with BIMA grafting (relative risk 3.24,95% CI: 1.54–6.83), correlating with more aggressive retraction during the procedure. 1 BIMA harvesting adds approximately 23 minutes to operative time, prolonging the duration of potentially injurious positioning. 1
At 7 weeks post-operatively, this patient is within the expected timeframe for persistent neurapraxia symptoms, which typically resolve within 6-12 weeks for mild injuries. 1
Critical Differential Diagnoses to Exclude First
Cardiac Ischemia (Must Rule Out)
- Post-CABG patients have twice the incidence of adverse cardiac events compared to non-CABG patients, with graft failure occurring in 10-20% at 1 year. 1
- While internal mammary artery grafts have superior patency (90-95% at 10-15 years) 1, 2, making graft-related vascular compromise to the upper extremities extremely rare, cardiac ischemia presenting with atypical symptoms must be excluded first. 3
- Obtain ECG looking for new ischemic changes and check cardiac biomarkers (troponin) to exclude acute myocardial injury. 3
Vascular Compromise
- Although IMA grafts demonstrate better patency than vein grafts after 10 years 2, assess bilateral radial and ulnar pulses and blood pressure in both arms to exclude subclavian or axillary artery compromise. 1
Diagnostic Workup Algorithm
Immediate Assessment (First Visit)
- Complete neurological examination focusing on dermatomal sensory distribution (C5-T1) to localize the level of nerve injury. 1
- Vascular assessment including bilateral radial and ulnar pulses, blood pressure in both arms, and capillary refill. 1
- ECG and cardiac biomarkers to exclude cardiac ischemia. 3
If Neurological Examination Confirms Peripheral Nerve Pattern
- Do NOT order EMG/nerve conduction studies in the first 2-3 weeks post-surgery, as they will be falsely negative. 1
- At 7 weeks post-op, EMG/NCS can now be performed if diagnosis is uncertain or symptoms are severe, but clinical diagnosis is usually sufficient. 1
Management Strategy
Symptomatic Treatment
Neuropathic pain management with gabapentin (starting 300 mg daily, titrating to 900-3600 mg/day in divided doses), pregabalin (starting 75 mg twice daily, titrating to 150-300 mg twice daily), or duloxetine (30-60 mg daily) is recommended. 1
Do NOT prescribe NSAIDs for pain management in post-CABG patients due to FDA contraindication. 1
Physical Therapy
- Gentle range-of-motion exercises to prevent contractures while awaiting nerve recovery. 1
- Occupational therapy for adaptive strategies if symptoms persist beyond 3 months. 1
Prognosis and Expected Recovery Timeline
Most brachial plexus injuries from surgical positioning are neurapraxias that resolve spontaneously within 3-6 months. 1
Recovery Timeline by Injury Severity
- Neurapraxia (most common): Complete recovery in 6-12 weeks. 1
- Axonotmesis (moderate injury): Recovery over 3-6 months as axons regenerate at 1 mm/day. 1
- Neurotmesis (complete nerve transection): Rare in positioning injuries; would require surgical intervention. 1
At 7 weeks post-op, this patient should be counseled that symptoms are expected to improve over the next 1-5 weeks if neurapraxia, or may persist for several more months if axonotmesis.
Follow-Up Schedule
- Reassess at 12 weeks (3 months) post-operatively. 1
- If no improvement by 3 months, obtain EMG/NCS and consider neurology referral. 1
- If progressive worsening or new motor weakness develops, expedite neurology evaluation. 1
Critical Pitfalls to Avoid
Do not dismiss upper extremity symptoms in post-CABG patients without first excluding cardiac ischemia. 1, 3 Post-CABG patients experience twice the incidence of adverse events (death, MI, recurrent angina) at 1 year compared to non-CABG patients. 3
Do not order EMG/nerve conduction studies in the first 2-3 weeks post-surgery, as they will be falsely negative. 1 At 7 weeks, these studies can be performed if needed, but clinical diagnosis is usually sufficient.
Do not prescribe NSAIDs for pain management in post-CABG patients. 1 Use gabapentinoids or SNRIs instead for neuropathic pain.
Do not assume bilateral symptoms exclude brachial plexus injury. 1 Bilateral IMA harvesting can cause bilateral nerve stretch injuries due to positioning of both arms during the procedure.