What is the recommended dose of ibuprofen (nonsteroidal anti-inflammatory drug (NSAID)) for a 7-year-old patient weighing 73 pounds (approximately 33 kilograms)?

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Ibuprofen Dosing for a 7-Year-Old Weighing 73 Pounds

For a 7-year-old child weighing 73 pounds (33 kg), administer ibuprofen at 10 mg/kg per dose, which equals 330 mg per dose, given every 6-8 hours as needed, not exceeding 4 doses (1,320 mg) in 24 hours.

Weight-Based Dosing Calculation

  • The effective dose range for ibuprofen in children is 7.5-10 mg/kg per dose, with clinical trials demonstrating optimal efficacy at the higher end of this range 1
  • For this 33 kg child, using 10 mg/kg yields 330 mg per dose 1
  • This dose can be administered every 6-8 hours, with a maximum of 3-4 doses in 24 hours 2
  • The maximum total daily dose should not exceed 40 mg/kg/day (1,320 mg for this child) 2

Practical Dosing Recommendations

  • Round to available formulations: 330 mg can be achieved using standard pediatric ibuprofen formulations (e.g., three 100 mg chewable tablets or 16.5 mL of 100 mg/5 mL suspension)
  • The minimum effective single dose is 200 mg, but this would be subtherapeutic for a child of this weight 3
  • Maximum antipyretic and analgesic effect occurs 3-4 hours after administration 1
  • Duration of action is approximately 6 hours, which is longer than paracetamol (4-6 hours) 3

Safety Considerations

  • Ibuprofen has a favorable safety profile in children and is better tolerated than in adults 1
  • Short-term use (up to 48 hours) is considered safe when attention is given to hydration status 2
  • The drug is safer in overdose than paracetamol or aspirin 1
  • Common adverse effects include gastrointestinal discomfort, though these are less frequent in children than adults 1

Common Pitfalls to Avoid

  • Do not underdose: Using adult OTC dosing (200 mg) would provide only 6 mg/kg, which is below the therapeutic range for this child's weight 3, 1
  • Track all doses carefully: Parents should record each dose time to avoid exceeding the maximum of 4 doses in 24 hours 4
  • Ensure adequate hydration: Special attention must be given to fluid intake, particularly if the child has fever or reduced oral intake 2
  • Avoid rectal administration: The rectal route has erratic absorption, especially in younger children, and should be avoided 2

References

Research

A general overview of the use of ibuprofen in paediatrics.

International journal of clinical practice. Supplement, 2003

Research

Review of the analgesic efficacy of ibuprofen.

International journal of clinical practice. Supplement, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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