What is the diagnosis for a 42-year-old male patient presenting with right hip pain, tenderness, and a palpable mass, with ultrasound (US) findings of a 2.6 x 0.9 x 1.6 cm ovoid shaped heterogeneous mass suspected to represent a lipoma, and a 1.1 x 0.7 x 1.3 cm lymph node located inferiorly to the suspected lipoma?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Right Hip Pain

The patient presents with right hip pain that worsens with walking, exercise, and sleeping, along with tenderness and pain upon palpation. The ultrasound findings reveal a suspected lipoma and a lymph node. Considering these details, the differential diagnosis can be categorized as follows:

  • Single Most Likely Diagnosis
    • Lipoma: The ultrasound finding of a 2.6 x 0.9 x 1.6 cm ovoid shaped heterogeneous mass suspected to represent a lipoma is the most direct evidence for this diagnosis. Lipomas are common, benign tumors composed of fat tissue and can cause pain and discomfort, especially if they are large enough to press on surrounding structures or if they become inflamed.
  • Other Likely Diagnoses
    • Bursitis: Given the location and the symptoms of pain with movement and tenderness, bursitis (inflammation of the bursae, which are fluid-filled sacs that cushion bones, tendons, and muscles near joints) is a plausible diagnosis. The presence of a lymph node could be secondary to inflammation.
    • Tendinitis: Inflammation of the tendons around the hip could cause pain, especially with activity. The lymph node could be reactive to the inflammation.
    • Soft Tissue Sarcoma: Although less common, a soft tissue sarcoma could present similarly to a lipoma but would be more concerning due to its malignant nature. The heterogeneous appearance on ultrasound might raise suspicion, but further imaging and biopsy would be necessary for diagnosis.
  • Do Not Miss Diagnoses
    • Bone or Soft Tissue Malignancy: It's crucial not to miss a malignant tumor, such as osteosarcoma, Ewing's sarcoma, or a soft tissue sarcoma like liposarcoma, which could present with similar symptoms and findings. The presence of a lymph node could indicate metastasis.
    • Infection or Abscess: An infected bursa, abscess, or osteomyelitis (bone infection) could cause severe pain, tenderness, and might be associated with a reactive lymph node. These conditions require prompt diagnosis and treatment to avoid serious complications.
  • Rare Diagnoses
    • Nerve Sheath Tumor: A benign or malignant tumor arising from the nerve sheath could cause pain and might be found incidentally on imaging. These are less common than lipomas but could explain the symptoms if the tumor is pressing on nearby nerves.
    • Pigmented Villonodular Synovitis (PVNS): A rare condition characterized by inflammation and overgrowth of the joint lining, leading to pain and swelling. It's less likely given the ultrasound findings but could be considered if other diagnoses are ruled out.

Each of these diagnoses has a different approach to management and treatment, ranging from watchful waiting for a benign lipoma to urgent surgical intervention for certain malignancies or infections. Further diagnostic workup, including potentially MRI for better soft tissue characterization and biopsy if a malignancy is suspected, would be essential to determine the exact cause of the patient's symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.