How many grams of carbohydrates are administered in 24 hours with D10 (10% dextrose solution) at 75 mL/hr?

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D10 at 75 mL/hr Delivers 180 Grams of Carbohydrates in 24 Hours

D10 (10% dextrose) contains 10 grams of dextrose per 100 mL, so at 75 mL/hr for 24 hours, you deliver 180 grams of carbohydrates total. 1, 2

Calculation Breakdown

  • D10 concentration: 10 grams of dextrose per 100 mL 2
  • Hourly delivery at 75 mL/hr: 7.5 grams per hour (75 mL × 0.1 g/mL) 1
  • 24-hour total: 180 grams (7.5 g/hr × 24 hours) 1, 2

Clinical Context for This Rate

  • The standard D10 infusion rate recommended by the American College of Clinical Endocrinology is 50 mL/hour (5 grams/hour) when tube feeding is interrupted in diabetic patients receiving insulin coverage 1
  • Your rate of 75 mL/hr delivers 7.5 grams/hour, which is 50% higher than the standard prevention rate 1
  • This 180 grams over 24 hours provides approximately 720 kcal of energy (dextrose provides 4 kcal/gram), representing partial nutritional support but insufficient as sole nutrition 2

Important Monitoring Considerations

  • Blood glucose should be monitored every 1-2 hours during continuous dextrose administration 1
  • This rate is appropriate for preventing hypoglycemia in patients receiving basal insulin when enteral nutrition is interrupted, particularly critical for type 1 diabetics 1
  • The American Diabetes Association emphasizes that type 1 diabetic patients require continuous basal insulin even when not receiving nutrition, making continuous D10 infusion essential to prevent hypoglycemia 1

Common Pitfall to Avoid

  • Never stop basal insulin in type 1 diabetics even when nutrition is interrupted—this is when D10 infusion becomes critical 1

References

Guideline

Administration of Dextrose Fluids in Diabetic Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Dextrose Administration Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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