What is the recommended dose of paracetamol (acetaminophen) for a 7-month-old patient weighing 7.2 kg using a paracetamol solution of 160 mg/5 mL?

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Dosis de Paracetamol para Lactante de 7 Meses

Para un lactante de 7 meses con peso de 7.2 kg usando jarabe de paracetamol 160 mg/5 mL, la dosis recomendada es 10-15 mg/kg por dosis cada 4-6 horas, lo que equivale a 72-108 mg por dosis, o aproximadamente 2.25-3.4 mL del jarabe.

Cálculo de la Dosis

  • Dosis estándar pediátrica: 10-15 mg/kg por dosis cada 4-6 horas 1
  • Para este paciente de 7.2 kg:
    • Dosis mínima: 7.2 kg × 10 mg/kg = 72 mg
    • Dosis máxima: 7.2 kg × 15 mg/kg = 108 mg

Conversión a Volumen del Jarabe

  • Concentración disponible: 160 mg/5 mL = 32 mg/mL 2
  • Volumen a administrar:
    • Para 72 mg: 72 mg ÷ 32 mg/mL = 2.25 mL
    • Para 108 mg: 108 mg ÷ 32 mg/mL = 3.4 mL

Recomendación práctica: Administrar 2.5-3 mL cada 4-6 horas según necesidad para dolor o fiebre.

Dosis Máxima Diaria

  • Límite diario: No exceder 75 mg/kg/día en lactantes 1
  • Para este paciente: 7.2 kg × 75 mg/kg = 540 mg/día máximo
  • Esto equivale a: Aproximadamente 17 mL del jarabe en 24 horas
  • Frecuencia segura: Máximo 4-5 dosis al día con intervalo mínimo de 4 horas entre dosis

Consideraciones Importantes

  • El paracetamol es seguro y efectivo como analgésico y antipirético en lactantes cuando se usa en dosis terapéuticas 3, 4
  • La toxicidad hepática es extremadamente rara con dosis terapéuticas y ocurre típicamente solo con sobredosis que exceden significativamente las dosis recomendadas 5, 3
  • Administrar con o sin alimentos; puede darse con comida si hay molestias gastrointestinales 6

Advertencias Críticas

  • Nunca exceder 75 mg/kg/día en lactantes para evitar riesgo de hepatotoxicidad 1, 5
  • Verificar que no se estén administrando otros medicamentos que contengan paracetamol simultáneamente 7
  • Si la fiebre o el dolor persisten más de 3 días, se requiere evaluación médica 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Injectable Paracetamol Dosing in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Acetaminophen: a practical pharmacologic overview.

Canadian Medical Association journal, 1984

Research

Acetaminophen Poisoning.

Critical care clinics, 2021

Research

Acetylsalicylic acid and acetaminophen.

Dental clinics of North America, 1994

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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