What are the risk factors, prevention strategies, signs, symptoms, and treatment options for Vasa Previa (Placental Vessel Prolapse)?

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Last updated: February 15, 2025View editorial policy

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From the Research

Introduction to Vasa Previa

Vasa previa, also known as placental vessel prolapse, is a rare and potentially life-threatening condition for the fetus, where unprotected fetal vessels run through the membranes over the cervix [ 1, 2 ].

Risk Factors

Several risk factors have been identified for vasa previa, including:

  • Second-trimester placenta previa and low-lying placentas
  • Velamentous cord insertion
  • Placentas with accessory lobes
  • In vitro fertilization
  • Multifetal gestations [ 2, 3 ]

Prevention Strategies

Prevention of vasa previa involves early prenatal diagnosis using ultrasound and color Doppler imaging [ 1, 4 ].

Signs and Symptoms

The signs and symptoms of vasa previa may not be apparent until the membranes rupture, at which point fetal exsanguination can occur [ 2 ].

Diagnosis

Diagnosis of vasa previa is made by visualization of velamentous fetal vessels coursing within the membranes over the cervix unprotected by Wharton jelly or placenta [ 3 ].

Treatment Options

Treatment options for vasa previa include:

  • Hospitalization or management as outpatients
  • Cesarean delivery in a tertiary center with experienced clinicians [ 1, 4 ]
  • Elective cesarean section prior to membrane rupture [ 5 ]
  • Close surveillance and appropriately timed late preterm delivery by cesarean [ 3 ]

Management Considerations

Management strategies for vasa previa depend on each institutional policy and may involve:

  • Inpatient management for patients with complications
  • Outpatient management for carefully selected asymptomatic patients [ 5 ]

Dosing and Duration

There is no specific dosing information relevant to the treatment of vasa previa.

Differential Diagnosis

Differential diagnosis for vasa previa includes other placental abnormalities, such as placenta previa.

Caveats

It is essential to note that outcomes continue to be dismal when vasa previa is undiagnosed before labor [ 2 ]. Therefore, early prenatal diagnosis and appropriate management are crucial to reduce the risks associated with vasa previa.

References

Research

Vasa Previa.

Obstetrics and gynecology, 2023

Research

Evidence-based Diagnosis and Treatment of Vasa Previa.

Clinical obstetrics and gynecology, 2025

Research

Guideline No. 439: Diagnosis and Management of Vasa Previa.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2023

Research

Management of vasa previa during pregnancy.

Journal of perinatal medicine, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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