What are the potential drug interactions between semaglutide (GLP-1 receptor agonist) and indapamide (thiazide-like diuretic) in an adult patient with type 2 diabetes and possible hypertension?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board

Educational purpose only • Exercise caution as content is pending human review

Article Review Status

Submitted

Under Review

Approved

Last updated: January 29, 2026 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

Is Rybelsus (semaglutide) a suitable treatment option for a patient with type 2 diabetes, obesity, and a history of cardiovascular disease, severe hypertension, and impaired renal function, for improving glycemic control and facilitating weight loss?

What is the best course of action for a middle-aged male with diabetes mellitus, hyperlipidemia, hypertension, fatty liver, and hypogonadism, who is experiencing adverse effects from Ozempic (semaglutide) 1 mg SQ once a week, and has elevated total cholesterol and LDL levels, while also facing issues with insurance coverage for Repatha (evolocumab)?

What is the best course of action for a male patient with diabetes (Diabetes Mellitus), hypertension, and hyperlipidemia, who has an elevated Hemoglobin A1c (HbA1c) level, impaired lipid profile, and is currently taking Ozempic (Semaglutide) 1 mg subcutaneously (SQ) once a week and atorvastatin (Atorvastatin) 20 mg once a day?

What alternative treatment options are available for a patient with type 2 diabetes and impaired renal function who experienced vision changes while on Ozempic (semaglutide)?

How should I adjust therapy for a 70‑year‑old man with type 2 diabetes, hypertension, hyperlipidemia, stage 3 chronic kidney disease, worsening glycemic control, elevated blood pressure, and overweight who is on atenolol, semaglutide (Ozempic), insulin glargine (Lantus), glipizide XL (Glucotrol XL), and losartan‑hydrochlorothiazide?

What are the considerations for using medetomidine for sedation in an adult patient without significant cardiovascular or respiratory comorbidities?

What is the best treatment approach for a patient with overactive bladder?

What is the initial approach to treating a patient diagnosed with hospital-acquired pneumonia (HAP)?

What follow-up questions should be asked to a 4-week post-myomectomy patient with a history of fibroids to assess their recovery progress and identify potential complications?

What is the best course of action for a patient on liothyronine (triiodothyronine) 25mcg with severely elevated Thyroid-Stimulating Hormone (TSH) levels and low thyroxine (T4) levels?

Can droxydopa and midodrine be given concurrently to a patient with orthostatic hypotension, particularly those with a history of conditions like Parkinson's disease or multiple system atrophy?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.