Ozempic Pen Dosing Calculation
35 clicks on a 1 mg Ozempic pen delivers 0.875 mg of semaglutide.
Understanding the Ozempic Pen Mechanism
The Ozempic pen is designed with a click-based dosing system where each click represents a specific increment of medication. For the 1 mg pen formulation:
- Each click delivers 0.025 mg of semaglutide 1
- The pen allows for precise dose adjustments in these small increments
- 35 clicks × 0.025 mg per click = 0.875 mg total dose
Clinical Context for This Dose
This 0.875 mg dose falls between the standard maintenance doses used in clinical practice:
- Standard type 2 diabetes dosing starts at 0.25 mg weekly, escalates to 0.5 mg weekly after 4 weeks, then to 1.0 mg weekly (the typical maintenance dose) 1
- The 0.875 mg dose represents approximately 87.5% of the standard 1.0 mg maintenance dose
- This intermediate dosing may be used when titrating between 0.5 mg and 1.0 mg if a patient experiences tolerability issues at the full 1.0 mg dose
Important Dosing Considerations
For type 2 diabetes treatment, the approved Ozempic dosing is 0.25 mg once weekly for 4 weeks, then 0.5 mg once weekly, with potential escalation to 1.0 mg weekly if additional glycemic control is needed 1. Some patients may require 2.0 mg weekly as a maximum dose.
For weight management (Wegovy formulation), semaglutide follows a different titration schedule starting at 0.25 mg weekly and escalating over 16 weeks to a maintenance dose of 2.4 mg weekly 2, 3.
Common pitfall: Do not confuse Ozempic (approved for type 2 diabetes with doses up to 2.0 mg weekly) with Wegovy (approved for weight management with doses up to 2.4 mg weekly) - they are the same molecule but different formulations with different approved indications 4, 5.