From the FDA Drug Label
Each tablet contains 324mg of ferrous sulfate, equivalent to 65mg of elemental iron, The amount of iron in one tablet of Optifer A (ferrous sulfate) is 65mg of elemental iron 1.
From the Research
Optifer A contains 100 mg of elemental iron per tablet, in the form of ferrous fumarate, a well-absorbed iron salt commonly used in iron supplements. This information is crucial for understanding the dosage and potential effects of Optifer A in treating or preventing iron deficiency anemia. The presence of vitamin C (ascorbic acid) in each tablet enhances iron absorption in the digestive tract, which is beneficial for patients with iron deficiency. Optifer A is typically prescribed with common dosing being one tablet once or twice daily, depending on the severity of the deficiency.
Key Points About Optifer A and Iron Supplementation
- Iron supplements like Optifer A work by replenishing iron stores in the body, essential for hemoglobin production and oxygen transport.
- For optimal absorption, it's best taken on an empty stomach, though it may be taken with food if stomach upset occurs.
- Side effects may include constipation, dark stools, and stomach discomfort, which are common with most iron supplements.
- The choice between oral iron supplements like Optifer A and intravenous iron therapy depends on several factors, including the presence of inflammation, the time available for iron replenishment, and the anticipated risk of side-effects or intolerance, as discussed in studies such as 2.
Considerations for Iron Deficiency Treatment
Given the information from studies like 3, which discusses the benefits of higher cumulative doses of intravenous iron for patients with iron deficiency anemia, and 4, which outlines the safety and efficacy of modern intravenous iron formulations, it's clear that the approach to iron deficiency treatment must be tailored to the individual patient's needs and circumstances. The most recent and highest quality studies, such as 5, support the efficacy and safety of intravenous iron therapy for managing iron deficiency anemia, especially in cases where oral iron supplements are ineffective or not tolerated.
Recommendations for Optifer A Use
Based on the most recent evidence, Optifer A is a viable option for patients with iron deficiency anemia who can tolerate oral iron supplements. However, for patients who require rapid correction of iron deficiency or have conditions that make oral iron supplementation ineffective, intravenous iron therapy may be preferred, as indicated by studies like 6 and 4. It's essential to weigh the benefits and potential risks of each treatment approach, considering the individual patient's health status, the severity of iron deficiency, and the potential for side effects, as discussed in 2 and 5.