From the Research
Sudafed (pseudoephedrine) is not the preferred choice for lactation suppression, as cabergoline has been shown to be more effective in recent studies. According to a randomized controlled trial published in 2024 1, cabergoline was superior to pyridoxine in inhibiting lactation, with a success rate of 78% compared to 35% for pyridoxine. This study suggests that cabergoline is a more effective option for lactation suppression.
Lactation Suppression Options
- Cabergoline: a dopamine agonist that has been shown to be effective in lactation suppression, with a success rate of 78% in a recent study 1.
- Pyridoxine (vitamin B6): may be considered for women with contraindications to cabergoline, as it has been shown to be effective in some studies, although with a lower success rate than cabergoline 1.
- Non-pharmacological methods: such as avoiding breast stimulation, wearing a supportive bra, and applying cold compresses, may also help reduce milk production.
Important Considerations
- Cabergoline has been associated with fewer rebound symptoms and adverse effects compared to other pharmacologic agents, such as bromocriptine 2.
- Women with contraindications to cabergoline, such as hypertensive disorders or fibrotic, cardiac, or hepatic diseases, may need to consider alternative options for lactation suppression.
- It is essential to consult with a healthcare provider to determine the best approach for lactation suppression, as individual circumstances and medical history may influence the choice of treatment.