Are parents of children of the same gender at a higher risk for postpartum depression (PPD)?

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Last updated: January 30, 2026View editorial policy

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Gender of Children and Postpartum Depression Risk

Having children all of the same gender does NOT increase postpartum depression risk in most populations, except in specific cultural contexts where male children are strongly preferred over female children.

Evidence from Cultural Contexts

The relationship between child gender and postpartum depression is primarily culturally mediated rather than biologically determined:

  • In cultures that differentially value male versus female children, having a female infant has been associated with increased PPD risk 1
  • In-law preference for a male child has also been linked to elevated PPD risk in these same cultural contexts 1
  • The mechanism appears to be reduced family support rather than the child's gender itself - when families express disappointment about having a female child, mothers receive less emotional and practical support, which is a well-established risk factor for PPD 1

Protective Effect of Male Gender in Some Studies

Interestingly, one large European study found the opposite pattern:

  • Male child gender was identified as a protective factor against prenatal depression in the Czech ELSPAC study (n=3,233) 2
  • This finding was significant in multivariate analysis controlling for other risk factors 2
  • However, this protective effect was not consistently found at postpartum timepoints 2

The Real Risk Factors for PPD

Rather than focusing on child gender composition, clinicians should assess the established major risk factors that consistently predict PPD across populations:

Strongest Predictors:

  • Personal history of depression or psychiatric illness 3, 2, 4
  • Depressive or anxiety symptoms during pregnancy 3, 4, 5
  • Lack of partner support and poor relationship quality 1, 6, 7, 8
  • Inadequate family support, especially from the woman's own mother 1, 6, 7, 8
  • Psychosocial stressors and stressful life events 8, 2, 5

Additional Significant Factors:

  • Gestational diabetes 3
  • Complications during pregnancy or delivery 3, 5
  • Low socioeconomic status 3, 2
  • History of intimate partner violence or abuse 1
  • Low prenatal attachment to the child 5

Clinical Implications

Do not screen for or counsel about child gender as a PPD risk factor in Western populations. Instead:

  • Focus screening efforts on the validated risk factors listed above 6, 8, 3
  • In culturally diverse populations, assess family attitudes about child gender preferences and their impact on family support systems 1
  • Strengthen partner and family support regardless of child gender, as this is consistently protective 1, 6, 7, 8
  • Use validated screening tools like the Edinburgh Postnatal Depression Scale (EPDS) with scores ≥10-11 indicating need for further evaluation 8

Common Pitfall to Avoid

Do not assume that having multiple children of the same gender creates inherent PPD risk. The evidence shows this is only relevant in specific cultural contexts where gender preference exists and manifests as reduced family support. The quality of relationships and support systems matters far more than the gender composition of children 1, 6, 7, 8.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Depression during pregnancy and postpartum.

Clinical obstetrics and gynecology, 2012

Guideline

Postpartum Depression and Anxiety Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Postpartum Depression with Neuropsychiatric Lupus History

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Postpartum Blues Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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