Treatment of Laryngitis
For acute laryngitis, provide symptomatic treatment with voice rest, adequate hydration, and analgesics while avoiding antibiotics and systemic corticosteroids, as these medications provide no benefit for viral laryngitis and carry significant risks. 1, 2
Initial Assessment
When evaluating a patient with laryngitis, immediately assess for:
- Life-threatening airway obstruction (epiglottitis or severe laryngeal edema with decreased air entry) requiring emergency intervention 3
- Duration of symptoms to classify as acute (<3 weeks) versus chronic (>3 weeks) 4, 5
- Viral etiology indicators including cough, rhinorrhea, and recent flu-like illness, which strongly suggest viral laryngitis 6, 1
- Red flags such as progressive worsening, signs of airway compromise, or symptoms persisting beyond 2-3 weeks requiring additional evaluation 1
First-Line Treatment for Acute Laryngitis
The cornerstone of management is conservative therapy:
- Voice rest to reduce vocal fold irritation and promote healing 1, 2, 3
- Adequate hydration to maintain mucosal moisture and reduce irritation 1, 2, 3
- Analgesics/antipyretics (acetaminophen or NSAIDs) for pain or fever relief 1, 2, 3
- Avoid both loud speaking and whispering, as both strain the vocal cords 1, 3
Acute viral laryngitis typically resolves within 7-10 days even with placebo treatment, and improvement occurs within 1-3 weeks in most cases. 1, 2
Medications to Avoid
Antibiotics
Do not prescribe antibiotics for viral laryngitis. 1, 2, 3 The evidence is clear:
- Antibiotics show no effectiveness in treating acute viral laryngitis 1
- They contribute to bacterial antibiotic resistance 1, 2
- They increase healthcare costs unnecessarily 1
- They may cause side effects including laryngeal candidiasis 1
Systemic Corticosteroids
Do not routinely prescribe systemic corticosteroids for laryngitis. 1, 2 The rationale:
- Lack of supporting evidence for efficacy 1, 2
- Significant adverse effects including cardiovascular disease, hypertension, osteoporosis, cataracts, impaired wound healing, infection risk, and mood disorders 1, 2
Exception: Systemic steroids are indicated for pediatric croup with associated hoarseness, where they have shown better outcomes. 1
Management of Chronic Laryngitis (>3 Weeks)
The Critical 4-Week Decision Point
Perform laryngoscopy at 4 weeks if symptoms persist to visualize the larynx and vocal folds. 2 This timing represents the optimal balance between:
- Allowing spontaneous resolution of viral laryngitis (typically 1-3 weeks) 2
- Preventing diagnostic delay for serious conditions including malignancy 2, 4
Earlier laryngoscopy is indicated for:
- Professional voice users with significant work impairment 2
- Any patient with progressive worsening or airway compromise 1
Post-Laryngoscopy Management
Anti-reflux therapy should only be considered if laryngoscopy demonstrates inflammatory findings (erythema, edema, redundant tissue, or surface irregularities of the vocal folds or arytenoid mucosa). 6, 2
Do not prescribe anti-reflux medications empirically for hoarseness without:
The evidence shows no benefit of empiric PPI therapy for hoarseness without documented reflux laryngitis, and PPIs carry significant risks including decreased calcium absorption, increased hip fracture risk, vitamin B12 deficiency, and iron deficiency anemia. 6, 1
Common Pitfalls to Avoid
- Do not use colored mucus as an indication for antibiotics - it does not differentiate viral from bacterial infection 3
- Do not prescribe sequential antibiotics for postinfectious cough, as this promotes antibiotic resistance without clinical benefit 3
- Do not use heartburn measurement tools to assess laryngeal symptoms, as these are not validated for dysphonia, cough, or throat symptoms 2
- Do not assume simple laryngitis in patients with decreased air entry without first excluding serious airway compromise 3
Patient Education
Counsel patients on:
- The viral nature of most laryngitis cases and expected 1-3 week resolution time 1, 2
- Voice conservation techniques and adequate hydration 1, 2
- Why antibiotics and steroids provide no benefit for typical viral laryngitis 1, 2
- The need for laryngoscopy if symptoms persist beyond 3-4 weeks to identify underlying causes 2