From the Research
Effect of Citric Acid on Adderall
There are no research papers to assist in answering this question, as none of the provided studies investigate the effect of citric acid on Adderall (amphetamine and dextroamphetamine).
Available Information on Adderall
- The provided studies discuss the pharmacology, efficacy, and safety of amphetamine preparations, including Adderall, in the treatment of attention-deficit/hyperactivity disorder (ADHD) 1, 2, 3, 4, 5.
- Adderall is a mixed amphetamine salts compound that contains dextroamphetamine and levoamphetamine, and is used to treat ADHD and narcolepsy 3, 5.
- The studies examine the clinical outcomes, pharmacodynamics, and adverse effects of amphetamine preparations, but do not mention the effect of citric acid on Adderall 1, 2, 4, 5.
Mechanism of Action of Amphetamine
- Amphetamine stimulates the release of norepinephrine, affecting both α- and β-adrenergic receptor sites, which can lead to increased heart rate, blood pressure, and skeletal muscle blood flow 3, 4.
- The different isomers of amphetamine (dextroamphetamine and levoamphetamine) may have distinct effects on dopamine release in the brain, which could influence their clinical effects 4.
Note: The provided studies do not investigate the effect of citric acid on Adderall, and therefore, no conclusions can be drawn on this topic.