What are the diagnostic tests for testicular pain (orchalgia)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Testicular pain should be evaluated promptly with a physical examination and diagnostic tests, including ultrasound, to determine the cause and prevent potential complications, with color Doppler ultrasound being particularly useful in diagnosing testicular torsion. When evaluating testicular pain, a thorough physical examination is essential, including inspection and palpation of the testicles, checking for swelling, tenderness, and masses 1. The diagnostic approach may involve urinalysis to check for infection, ultrasound to visualize the testicles and blood flow, and sometimes blood tests to check for infection markers or hormonal abnormalities. In cases of suspected testicular torsion, color Doppler ultrasound is the preferred diagnostic test due to its ability to evaluate testicular perfusion and detect reduced blood flow, which is critical for prompt intervention 1. The sensitivity and specificity of color Doppler US for the detection of testicular torsion can vary, but it remains a valuable tool in combination with clinical history and physical examination 1. Other causes of testicular pain, such as epididymitis, orchitis, trauma, hernias, or kidney stones, require different treatment approaches and can be differentiated with the help of ultrasound findings, including an enlarged and hypoechoic epididymis in epididymitis, and clinical correlation 1. Prompt evaluation and treatment are crucial, especially in cases of testicular torsion, where timely intervention can prevent permanent damage and improve outcomes 1.

From the Research

Testicular Pain Testing

  • Testicular torsion is a surgical emergency that requires prompt recognition and treatment to prevent complications such as testicular infarction, necrosis, and sub/infertility 2, 3.
  • The diagnosis of testicular torsion is typically made based on a combination of history, physical examination, and imaging studies such as Doppler ultrasound scan 4.
  • Patients with testicular torsion typically present with severe acute unilateral scrotal pain, nausea, and vomiting, and may have a high-riding testicle with an absent cremasteric reflex 2.
  • Epididymo-orchitis is another common cause of testicular pain, and is typically characterized by a gradual onset of scrotal pain and symptoms of lower urinary tract infection, including fever 5.
  • The differential diagnosis of testicular pain is crucial, and advanced practice nurses should consider testicular torsion in any patient with testicular pain, regardless of age, history, or physical examination findings 4.

Diagnostic Approaches

  • A thorough history and physical examination are essential in the diagnosis of testicular torsion and epididymo-orchitis 3, 5.
  • Imaging studies such as Doppler ultrasound scan can help confirm the diagnosis of testicular torsion 4.
  • Laboratory studies, including urethral Gram stain, urinalysis and culture, and polymerase chain reaction assay for C. trachomatis and N. gonorrhoeae, can help guide therapy for epididymo-orchitis 5.

Management Strategies

  • Prompt surgical exploration is indicated in cases of suspected testicular torsion, and should not be postponed to perform imaging studies 2.
  • Patients with epididymo-orchitis should be treated with empirical antibiotics that target the most common pathogens, such as ceftriaxone and doxycycline for C. trachomatis and N. gonorrhoeae, or ofloxacin or levofloxacin for coliform bacteria 5.
  • Immediate attention to testicular torsion and epididymo-orchitis is crucial to prevent complications and improve outcomes 2, 3, 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Presentation of Testicular Torsion in the Emergency Department.

Advanced emergency nursing journal, 2016

Research

Epididymitis and orchitis: an overview.

American family physician, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.