What is the amount of potassium in milliequivalents (mEq) in 1 liter of Plasma-Lyte R (PLR)?

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Potassium Content in Plasma-Lyte R

One liter of Plasma-Lyte R (PLR) contains 5 mEq of potassium. 1

Composition Details

  • Plasma-Lyte R contains exactly 5 mEq/L of potassium, as clearly documented in the American Academy of Pediatrics clinical practice guideline table comparing intravenous fluid compositions 1

  • The complete electrolyte composition of Plasma-Lyte R includes:

    • Sodium: 140 mEq/L 1
    • Potassium: 5 mEq/L 1
    • Chloride: 98 mEq/L 1
    • Magnesium: 3 mEq/L 1
    • Acetate buffer: 27 mEq/L 1
    • Osmolarity: 294 mOsm/L 1

Clinical Context

  • This potassium concentration of 5 mEq/L is physiologically similar to normal plasma potassium levels (3.5-5.3 mEq/L), making it a balanced crystalloid solution 1

  • The potassium content in Plasma-Lyte R should not be considered a contraindication even in patients with mild-to-moderate hyperkalemia or renal dysfunction, as large randomized studies involving 30,000 patients showed comparable plasma potassium concentrations between balanced fluids and normal saline 1

  • From a physiological standpoint, it is not possible to create potassium excess using a fluid with potassium concentration lower than or equal to the patient's plasma concentration 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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