What is the difference between aortic insufficiency and aortic regurgitation?

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Last updated: April 17, 2025View editorial policy

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From the Guidelines

There is no difference between aortic insufficiency and aortic regurgitation; they are two terms used to describe the same heart condition. Both refer to the backflow of blood from the aorta into the left ventricle during diastole due to incomplete closure of the aortic valve. This occurs when the aortic valve leaflets fail to seal properly, allowing blood that should be moving forward through the circulatory system to leak backward into the heart. The condition can be acute or chronic and varies in severity from mild to severe. The terminology choice often depends on physician preference or regional medical conventions, with "aortic regurgitation" being slightly more common in modern medical literature, as seen in the 2022 European Heart Journal study 1.

Key Points

  • Symptoms may include fatigue, shortness of breath, chest pain, and heart palpitations.
  • Treatment depends on severity and may include medications like ACE inhibitors or angiotensin receptor blockers to reduce afterload, or surgical valve repair or replacement for severe cases, as recommended by the 2021 American College of Cardiology/American Heart Association joint committee on clinical practice guidelines 1.
  • Regular monitoring with echocardiography is essential for patients with this condition to track progression and determine optimal timing for intervention.
  • The 2012 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure also support the importance of surgery in patients with severe aortic regurgitation and left ventricular dysfunction or dilatation 1.

Management and Treatment

The management of patients with aortic regurgitation depends on an accurate diagnosis of the severity of the condition, as outlined in the 2021 guidelines 1. Patients with severe aortic regurgitation may require surgical intervention, such as valve repair or replacement, to reduce the risk of death and heart failure. The choice of valve prosthesis and surgical technique depends on various factors, including the patient's age, lifestyle, and medical history, as discussed in the 2014 American Heart Association/American College of Cardiology guideline 1.

Conclusion is not allowed, so the answer will be ended here.

From the Research

Difference between Aortic Insufficiency and Aortic Regurgitation

  • Aortic insufficiency (AI) and aortic regurgitation (AR) are often used interchangeably, but they refer to the same condition: the leakage of the aortic valve, allowing blood to flow back from the aorta into the left ventricle 2.
  • The terms AI and AR describe the same valvular disease characterized by retrograde blood flow from the aorta to the left ventricle, with various etiologies resulting in either acute or chronic clinical presentations 3.
  • Both AI and AR can lead to heart failure symptoms due to left ventricular remodeling, and their diagnoses rely on similar methods, including electrocardiography, chest radiographs, and echocardiography 3, 2.
  • The management of chronic AR aims to control hypertension and delay left ventricular dysfunction, with medications such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and potentially calcium-channel blockers recommended for treatment 3, 4, 5.
  • The use of renin-angiotensin-aldosterone system blockade has been shown to improve outcomes in patients with AR, reducing all-cause mortality and cardiovascular events 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Aortic Regurgitation: Review of Current Management.

Dimensions of critical care nursing : DCCN, 2024

Research

Aortic insufficiency: defining the role of pharmacotherapy.

American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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