What is the best course of action for a 9-year-old girl with suspected appendicitis, presenting with right lower quadrant pain, normal white blood cell (WBC) count, no fever, no anorexia, and no rebound tenderness?

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Management of Low-Risk Suspected Appendicitis in a 9-Year-Old Girl

Discharge the patient with clear return precautions and mandatory 24-hour follow-up (Option C). This clinical presentation represents a low-risk scenario that does not warrant immediate imaging or hospital admission.

Risk Stratification

This patient's clinical profile places her in the low-risk category for acute appendicitis:

  • Normal WBC count (9,000/μL) combined with absence of fever significantly reduces the probability of appendicitis, with a negative predictive value of 97.3% when WBC is normal 1
  • Absence of rebound tenderness indicates no peritoneal irritation, a key finding in established appendicitis 2
  • Absence of anorexia further decreases the likelihood of appendicitis 2
  • The combination of fever, elevated WBC, and rebound tenderness creates a prediction rule with only 1% missed appendicitis rate in pediatric patients—this patient has none of these features 2

Why Not Admit for Observation (Option A)?

Admission with 24-hour observation is not indicated for low-risk patients, as it is resource-intensive and exposes the patient to unnecessary hospitalization costs and risks 2. The WSES Jerusalem Guidelines specifically recommend against admission for low-risk patients who can be safely discharged with return precautions 2.

Why Not CT Imaging (Option B)?

CT should be reserved for intermediate or high-risk patients, not reflexively ordered for all suspected appendicitis 2. In children with low clinical suspicion, CT exposes patients to unnecessary radiation without changing management 2. The American College of Radiology recommends a step-up approach tailored to clinical risk stratification 2.

Clinical scoring systems should guide imaging decisions, not reflexive CT ordering 2. Low-risk patients can be safely discharged with appropriate safety netting, avoiding unnecessary imaging and radiation exposure 2.

Recommended Management Algorithm

Immediate Actions:

  • Provide clear emergency return precautions: instruct the patient to return immediately if symptoms worsen, or if fever, vomiting, or increased abdominal tenderness develop 2
  • Maintain hydration while monitoring symptoms 2
  • Mild pain control, avoiding opioids which can mask symptoms 2

Mandatory Follow-Up:

  • Schedule follow-up within 24 hours to ensure resolution of symptoms 2
  • This is essential due to measurable false-negative rates in low-risk presentations 2
  • If symptoms persist or worsen at follow-up, proceed to imaging with ultrasound as first-line in pediatrics (sensitivity 76%, specificity 95%), followed by CT if ultrasound is inconclusive 2, 3

Critical Pitfalls to Avoid

  • Do not rely on absence of fever to exclude appendicitis—fever is absent in approximately 50% of appendicitis cases 2
  • Do not discharge without establishing a clear follow-up plan 2
  • NSAIDs can mask evolving symptoms and delay diagnosis, so use cautiously 2
  • Normal WBC does not completely exclude appendicitis but significantly reduces probability when combined with benign clinical presentation 4, 1

When to Escalate Care

If during the 24-hour observation period at home the patient develops:

  • Fever or worsening pain 2
  • Persistent vomiting 2
  • Development of peritoneal signs (guarding, rigidity, rebound tenderness) 2
  • Inability to tolerate oral intake 2

Then proceed immediately to emergency department evaluation with ultrasound imaging as first-line modality 2, 3.

References

Guideline

Management of Suspected Appendicitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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