From the Guidelines
Nystatin tablets are used to treat oropharyngeal candidiasis, a fungal infection of the mouth and throat.
Treatment Details
- The dosage of nystatin for oropharyngeal candidiasis is typically 200,000-400,000 U administered 5 times a day 1.
- Nystatin can be used as an alternative to clotrimazole troches or fluconazole for the treatment of mild oropharyngeal candidiasis 1.
- The treatment duration for oropharyngeal candidiasis with nystatin is usually 7-14 days 1.
Clinical Guidelines
- The Infectious Diseases Society of America recommends nystatin suspension or pastilles as a treatment option for oropharyngeal candidiasis 1.
- The ESCMID guideline for the diagnosis and management of Candida diseases recommends nystatin suspension for the treatment of oropharyngeal candidiasis in non-neutropenic patients with mild presentation 1.
- Nystatin is also suggested as a prophylactic agent for oral and esophageal Candida in kidney transplant recipients 1.
From the FDA Drug Label
INDICATIONS AND USAGE Nystatin Oral Suspension, USP, is indicated for the treatment of candidiasis in the oral cavity. The FDA drug label does not answer the question.
From the Research
Nystatin Tablets
Nystatin tablets are used to treat fungal infections, specifically:
- Oral fungal infections, such as candidiasis 2, 3
- Prevention of systemic candidosis in patients at particular risk, including immunocompromised individuals 4
Properties and Indications
The properties and indications of nystatin tablets include:
- Antifungal activity against Candida albicans and other fungal strains 5, 4
- Limited solubility and high toxicity, making it suitable for topical use only 5
- Effective in preventing the spread of Candida albicans from the orogastrointestinal tract 4
- Can be used in combination with other antifungal agents, such as chlorhexidine 3
Formulations and Delivery
Different formulations and delivery methods of nystatin tablets have been developed to improve their efficacy and safety, including: