Treatment of Vertigo
The treatment of vertigo depends critically on the underlying cause: canalith repositioning maneuvers (Epley or Semont) are first-line for BPPV with 80% success rates, while vestibular suppressant medications like meclizine should only be used short-term (3-5 days maximum) for severe acute symptoms and are NOT appropriate as primary treatment for most vertigo conditions. 1
Diagnosis-Specific Treatment Algorithm
For BPPV (Benign Paroxysmal Positional Vertigo)
Primary Treatment:
- Perform canalith repositioning maneuvers (Epley or Semont) as first-line therapy, achieving 78.6%-93.3% improvement compared to only 30.8% with medication alone 1
- Success rates reach approximately 80% with only 1-3 treatments 1
- The American Academy of Otolaryngology-Head and Neck Surgery explicitly recommends AGAINST routine use of vestibular suppressants for BPPV 1, 2
Limited Medication Role:
- Meclizine may ONLY be considered for severe nausea/vomiting during repositioning procedures, NOT as primary treatment 1
- Prochlorperazine 5-10 mg may be used for severe autonomic symptoms (maximum three doses per 24 hours) 3
- Medications can actually interfere with recovery and should be avoided as definitive therapy 1
For Ménière's Disease
Acute Attack Management:
- Use vestibular suppressants for SHORT-TERM relief only during acute attacks 4
- Meclizine 25-100 mg daily in divided doses, prescribed as-needed rather than scheduled 1, 5
- Limit use to 3-5 days maximum to avoid delaying vestibular compensation 3
Maintenance Therapy:
- Dietary sodium restriction to 1500-2300 mg daily 4, 3
- Diuretics may be offered for maintenance therapy to reduce attack frequency 4
- Betahistine may be considered, though the BEMED trial showed no significant benefit over placebo 1
Advanced Options for Refractory Cases:
- Intratympanic steroids for active disease not responsive to noninvasive treatment 4
- Consider intratympanic gentamicin or surgical options for severe, intractable cases 4
For Acute Vestibular Neuritis/Labyrinthitis
Immediate Management (First 3-5 Days):
- Meclizine 25-100 mg daily in divided doses, as-needed only 1, 5
- Prochlorperazine 5-10 mg for severe nausea/vomiting (maximum three doses per 24 hours) 3
- Short-term benzodiazepines (diazepam 10 mg) may be considered for severe vertigo with anxiety, though fall risk is significant in elderly 3
- Consider oral corticosteroids if inflammatory process is suspected 3
Critical Transition:
- STOP vestibular suppressants after 3-5 days 3
- Begin Vestibular Rehabilitation Therapy (VRT) as soon as acute symptoms are manageable (typically within 3-7 days) 3
- VRT is more effective than prolonged medication use for lasting symptom resolution 3
Medication Dosing and Safety
Meclizine (FDA-Approved)
- Dosing: 25-100 mg daily in divided doses 5
- Administration: Swallow tablets whole, use as-needed rather than scheduled 1, 5
- Contraindications: Hypersensitivity to meclizine or inactive ingredients 5
- Warnings: May cause drowsiness affecting driving ability; use with caution in asthma, glaucoma, or prostate enlargement 5
Critical Safety Warnings for All Vestibular Suppressants
Fall Risk:
- Vestibular suppressants are an independent risk factor for falls, particularly in elderly patients 1, 3
- Anticholinergic side effects include drowsiness, cognitive deficits, dry mouth, blurred vision, and urinary retention 1
Interference with Recovery:
- Long-term use (>3-5 days) interferes with central vestibular compensation, potentially prolonging overall recovery time 3
- Medications can decrease diagnostic sensitivity during Dix-Hallpike maneuvers 2
Vestibular Rehabilitation Therapy
Indications:
- Chronic imbalance following acute vestibular events 4
- Persistent symptoms after initial treatment 3
- Should NOT be used for acute vertigo attacks in Ménière's disease 4
Timing:
- Begin within 3-7 days of acute symptom onset 3
- More effective than prolonged medication use for long-term recovery 3
Lifestyle Modifications (All Vertigo Types)
- Limit sodium intake to 1500-2300 mg daily, especially for Ménière's disease 3
- Avoid excessive caffeine, alcohol, and nicotine 1, 3
- Maintain adequate hydration and regular sleep patterns 1, 3
- Implement stress management techniques 1, 3
- Regular exercise when tolerated 1
Follow-Up Protocol
- Reassess within 1 month to document symptom resolution or persistence 1, 3
- Discontinue vestibular suppressants as soon as possible 1
- If symptoms persist beyond 4-6 weeks despite appropriate treatment, consider alternative diagnoses (vestibular migraine, BPPV variants, bilateral vestibular hypofunction) 3
Common Pitfalls to Avoid
Do NOT:
- Use meclizine or other vestibular suppressants as primary treatment for BPPV 1, 2
- Prescribe vestibular suppressants on a scheduled basis—use as-needed only 1
- Continue vestibular suppressants beyond 3-5 days 3
- Use vestibular rehabilitation during acute Ménière's attacks 4
- Prescribe positive pressure therapy (Meniett device) for Ménière's disease—it is ineffective 4
Do: