From the Research
Pityriasis rosea typically resolves on its own without treatment within 6-8 weeks, so management focuses on symptom relief. For mild itching, over-the-counter antihistamines like diphenhydramine (25-50mg every 4-6 hours) or cetirizine (10mg daily) can help 1. Topical treatments include calamine lotion applied to affected areas 2-3 times daily or 1% hydrocortisone cream applied twice daily for up to two weeks to reduce inflammation and itching.
Key Considerations
- For more severe symptoms, a dermatologist may prescribe stronger corticosteroid creams or oral antihistamines.
- Lukewarm baths with colloidal oatmeal can soothe the skin.
- Patients should avoid hot showers, harsh soaps, and excessive sun exposure which can worsen symptoms.
- Wearing loose, cotton clothing helps prevent irritation.
Treatment Options
- While some studies suggest that erythromycin or UVB phototherapy may speed recovery in severe cases, evidence is limited 2, 3.
- Acyclovir may be considered for individuals with severe or recurrent pityriasis rosea and pregnant women with the disease 1, 4.
- The condition is believed to be triggered by a viral infection, particularly human herpesvirus 6 or 7, explaining why it typically doesn't recur and why treatment focuses on managing symptoms rather than the underlying cause.
Best Course of Action
- Given the most recent and highest quality study, the best approach is to focus on symptom relief and consider acyclovir for severe cases 1.