Generic Version of Anusol
The generic version of Anusol is hydrocortisone 1% topical preparation, available as cream, ointment, or suppository. 1
Active Ingredient and Formulations
- Anusol contains hydrocortisone 1% as its active ingredient, which is the generic name for this medication 1
- Hydrocortisone topical preparations are available over-the-counter in various formulations including creams, ointments, and suppositories for hemorrhoid treatment 2
Clinical Use for Hemorrhoids
- Hydrocortisone topical preparations provide symptomatic relief by reducing local perianal inflammation and irritation associated with hemorrhoids 2
- The medication works as a corticosteroid to ameliorate local inflammation, though it does not cure hemorrhoids or reduce hemorrhoidal swelling, bleeding, or protrusion 2
Critical Usage Limitations
- Hydrocortisone preparations must be limited to ≤7 days maximum duration to avoid thinning of perianal and anal mucosa 2
- Long-term use of corticosteroid suppositories is potentially harmful and should be avoided 2
- The FDA label specifically warns to stop use if symptoms persist for more than 7 days or clear up and occur again within a few days 1
Important Safety Considerations
- Do not use in the genital area if vaginal discharge is present 1
- Avoid contact with eyes and do not use more than directed 1
- Do not put directly into the rectum using fingers or any mechanical device 1
- Stop use and consult a doctor if condition worsens, symptoms persist beyond 7 days, or rectal bleeding occurs 1
Alternative Considerations
- For longer-term management, mesalamine (5-ASA) suppositories are more effective than hydrocortisone for symptom relief in hemorrhoid patients, with a relative risk of 0.74 (95% CI 0.61-0.90) 2
- Topical 0.3% nifedipine with 1.5% lidocaine ointment applied every 12 hours for two weeks shows superior efficacy (92% resolution rate) compared to other topical treatments for thrombosed external hemorrhoids 2