Proper Procedure for Administering Intramuscular (IM) Injections
Administer IM injections at a 90-degree angle perpendicular to the skin surface using the deltoid muscle in adults and the anterolateral thigh in infants, with needle length of 1-1½ inches (22-25 gauge) for adults and 7/8-1 inch for infants—never use the buttock due to sciatic nerve injury risk and decreased medication efficacy. 1, 2, 3
Site Selection by Age Group
Adults (>18 years)
- Use the deltoid muscle as the preferred site for routine IM injections, including vaccines and vitamin B12 1, 2, 3
- The anterolateral thigh is an acceptable alternative site if the deltoid is not suitable 1, 2
- Administer the injection 4 fingerbreadths (approximately 9 cm) below the mid-acromion point to avoid underlying neurovascular structures, particularly the axillary nerve and posterior circumflex humeral artery 4
- Never inject in the upper half of the deltoid muscle 4
Infants (<12 months)
- Use the anterolateral aspect of the thigh as the preferred site, which provides the largest muscle mass in this age group 1, 2, 3
- The deltoid muscle is not recommended due to inadequate muscle mass 1
Toddlers and Children (12 months to 18 years)
- Use the deltoid muscle if adequate muscle mass is present; otherwise, use the anterolateral thigh 1, 2, 3
- The anterolateral thigh remains the safer option for younger toddlers 3
Needle Specifications
Adults
- Needle length: 1 to 1½ inches (25-38 mm) 1, 2, 3
- Needle gauge: 22-25 gauge 1, 2, 3
- The needle must be long enough to reach muscle mass and prevent seepage into subcutaneous tissue, but not so long as to involve underlying nerves, blood vessels, or bone 1, 2
Infants
Toddlers and Children
Injection Technique
Angle of Insertion
- Insert the needle at a 90-degree angle perpendicular to the skin surface 1, 2, 3, 5
- This 90-degree angle is critical because deviating from the recommended route can reduce medication efficacy or increase local adverse reactions 1
- While one study suggests angles between 72-90 degrees may be acceptable, the standard guideline remains 90 degrees 6, 5
Volume Considerations
- Maximum volume for deltoid injections: 1-2 mL in adults 1
- For volumes >2 mL, use the anterolateral thigh or ventrogluteal site instead, as these sites have greater muscle mass 1
- Routine deltoid vaccinations typically use volumes of 0.5-1 mL 1
Multiple Injections
- When administering multiple IM injections in the same limb, separate injection sites by more than 1 inch (2.5 cm) to differentiate any local reactions 1
- Document the location of each injection in the medical record 1
Aspiration
- Aspiration before injection is not necessary, as no data support this as a required procedure according to the CDC 1
Critical Sites to Avoid
Never Use the Buttock
- The buttock should never be used for routine IM injections due to:
Other Sites to Avoid
- Areas with lipohypertrophy, scars, or tissue abnormalities should be avoided 2
- For insulin injections specifically, avoid a circle with a 2-inch radius around the navel 7
Common Pitfalls and How to Avoid Them
Inadequate Needle Length
- Using a needle that is too short results in subcutaneous rather than intramuscular delivery, reducing medication efficacy 1
- Always select needle length based on patient age, body size, and muscle mass 1, 2
Incorrect Site Selection
- Injecting into the buttock carries both safety risks (sciatic nerve injury) and efficacy concerns (decreased drug absorption) 1
- Always use the deltoid in adults or anterolateral thigh in infants unless contraindicated 1, 2, 3
Improper Angle
- Deviating from the 90-degree angle can reduce medication efficacy or increase adverse reactions 1
- Ensure the needle is inserted perpendicular to the skin surface 1, 2, 3