Why is the 5th intercostal space (ICs) at the mid-axillary line the preferred site for tube thoracostomy?

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Last updated: February 3, 2026View editorial policy

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Why the 5th Intercostal Space at the Mid-Axillary Line is Preferred for Tube Thoracostomy

The 5th intercostal space (ICS) at the mid-axillary line is the preferred site for tube thoracostomy because it provides the thinnest chest wall thickness (mean 3.5 cm ± 0.9 cm), achieves 100% successful pleural cavity penetration, and minimizes risk of injury to vital structures including the diaphragm, heart, and major vessels. 1, 2

Anatomical Advantages of the 5th ICS Mid-Axillary Line

Superior Success Rates

  • The 5th ICS at the mid-axillary line achieves 100% successful pleural cavity penetration compared to only 57.5% success at the traditional 2nd ICS midclavicular line. 2
  • The chest wall is significantly thinner at the 5th ICS (3.5 cm ± 0.9 cm) compared to the 2nd ICS (4.5 cm ± 1.1 cm), making tube insertion more reliable. 2, 3
  • This 1 cm difference in chest wall thickness translates to substantially improved procedural success, particularly in obese patients or those with increased body mass index. 2, 3

Safety Profile

  • The anterior to mid-axillary line between the 4th or 5th intercostal space contains no vital organs or organ structures except lung parenchyma when proper technique is used. 4
  • The v. thoracoepigastrica is the only significant vessel at the lateral thoracic wall, and it can be avoided by inserting above the superior rib margin. 4
  • For right-sided procedures, both the 5th ICS mid-axillary line and 2nd ICS midclavicular line are acceptable options. 5, 6
  • For left-sided procedures, the 2nd ICS midclavicular line is safer due to lower risk of cardiac injury, though the 5th ICS can be used on the right side. 5, 6

Critical Technical Considerations

Proper Insertion Technique

  • Insert the tube at the superior border of the rib to avoid the neurovascular bundle that runs along the inferior rib margin. 6
  • The insertion should be perpendicular to the chest wall at the 4th or 5th intercostal space in the mid- or anterior-axillary line. 1
  • Use blunt dissection rather than a steel trocar, as trocar insertion significantly increases complications including hemothorax, lung lacerations, and injury to thoracic or abdominal organs. 1

Ultrasound Guidance Strongly Recommended

  • Ultrasound should be used to identify the diaphragm position before insertion, as 20% of right hemidiaphragms and 18% of left hemidiaphragms are above or crossing the 5th ICS during the respiratory cycle. 7
  • Blind landmark-based approaches at the 5th ICS result in a significant percentage of subdiaphragmatic insertions or diaphragmatic injuries. 7
  • Ultrasound can identify safer insertion sites and reduce thoracostomy complications substantially. 7

Common Pitfalls and How to Avoid Them

Diaphragm Injury Risk

  • The most critical pitfall is inserting too low and penetrating the diaphragm or entering the abdominal cavity. 7
  • Always use ultrasound to visualize the diaphragm through an entire respiratory cycle before marking the insertion site. 7
  • If ultrasound is unavailable, err on the side of inserting one intercostal space higher (4th ICS) rather than risk subdiaphragmatic placement. 1

Patient-Specific Factors

  • Women have significantly thicker chest walls than men at both the 2nd ICS (52 mm vs 38 mm) and 5th ICS (38 mm vs 33 mm). 3
  • Patients with trauma, subcutaneous emphysema, multiple rib fractures, lung contusion, or sternum fractures have thicker chest walls at the 5th ICS. 3
  • Despite these variations, the 5th ICS remains thinner than the 2nd ICS in all patient subgroups. 3

Tube Size Considerations

  • Standard 5 cm catheters are inadequate for approximately 33% of women and 13% of men at the 5th ICS. 3
  • Use larger bore tubes (28-32 French) with adequate length to ensure pleural cavity access. 1

Distinction from Needle Thoracostomy

It is important to distinguish tube thoracostomy from needle thoracostomy (emergency decompression):

  • For needle decompression of tension pneumothorax, the American College of Surgeons recommends the 5th ICS at the anterior axillary line with a 7-8 cm needle. 8
  • Tube thoracostomy is the definitive treatment following needle decompression. 5, 8
  • The 5th ICS mid-axillary line serves as the optimal site for both procedures due to consistent anatomical advantages. 8, 1, 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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