From the FDA Drug Label
Uses temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: ... temporarily relieves external anal and genital itching
- Hydrocortisone cream can be used to relieve anal itch.
- It is recommended to use this product under the advice and supervision of a doctor for other uses. 1
From the Research
For anal itching caused by fungal infections, I strongly advise against using steroid-antifungal combination creams as a first-line treatment due to the potential risks associated with steroid use, as highlighted in the most recent study 2. Instead, consider using a topical antifungal agent, such as clotrimazole, as a primary treatment option. The use of corticosteroids in fungal diseases has been shown to be associated with a worse outcome in many cases, including increased mortality and worse visual outcome in fungal keratitis 2. However, if a steroid-antifungal combination cream is deemed necessary, I recommend using a product like Lotrisone (clotrimazole 1% and betamethasone 0.05%) or similar combinations applied thinly to the affected area twice daily for 7-14 days, with careful monitoring for potential side effects. It is essential to note that the use of corticosteroids should be minimized and avoided if possible, especially in invasive fungal diseases, as they can increase mortality and worsen outcomes 2. Before application, gently clean and dry the area, apply a small amount (pea-sized), and rub in completely, then wash hands thoroughly after application. If symptoms persist beyond two weeks, worsen, or if you develop bleeding, pain, or discharge, seek medical attention as this may indicate a different condition requiring alternative treatment. Keep the anal area clean and dry, wear loose cotton underwear, and avoid scratching to prevent worsening the condition or causing secondary infections. In general, antifungal combination therapy may be beneficial in certain cases of invasive fungal infections, such as cryptococcal meningitis, but more research is needed to confirm its effectiveness in other types of fungal infections 3. The most recent study on the topic 2 provides a comprehensive review of the impact of corticosteroids on fungal disease outcomes, highlighting the need for cautious use of these medications in patients with fungal infections.