Management of Bullous Myringitis
Bullous myringitis should be treated as a severe, painful variant of acute otitis media with the same antibiotics used for AOM, combined with aggressive pain management and consideration for myringotomy (opening the hemorrhagic bullae) in severe cases. 1
Clinical Recognition and Severity Assessment
Bullous myringitis presents with characteristic hemorrhagic vesicles on the tympanic membrane and medial external auditory canal wall, representing approximately 7-9% of acute otitis media cases. 2, 3
Key distinguishing features from standard AOM:
- More severe pain - often the dominant presenting symptom requiring aggressive management 1, 2
- More frequent fever (62% vs lower rates in standard AOM) 3
- Bulging tympanic membrane in non-bullous quadrants 2
- Higher symptom severity including excessive crying, restless sleep, and poor appetite 3
- Risk of sensorineural hearing loss - can occur in a subset of patients, though typically reversible 1, 4, 5
Middle ear fluid develops in 97% of cases during disease course, confirming this is fundamentally a manifestation of AOM rather than a distinct entity. 3
Immediate Management Algorithm
Step 1: Pain Control (Priority)
- Initiate aggressive analgesic therapy immediately - this is non-negotiable given the excessive pain characteristic of this condition 1, 2
- Standard pain management for severe AOM applies (acetaminophen, ibuprofen, topical anesthetics)
Step 2: Consider Myringotomy
- Opening hemorrhagic bullae may be necessary as a medical emergency for severe pain relief 1
- This intervention is particularly important when pain is refractory to standard analgesics
- The procedure provides immediate symptomatic relief
Step 3: Antibiotic Therapy
Treat with the same antibiotics as acute otitis media - the causative organisms are identical (S. pneumoniae, H. influenzae, M. catarrhalis). 1, 2
Standard first-line therapy:
- Amoxicillin or amoxicillin-clavulanate at standard AOM dosing
- Treatment duration and choice adapted to clinical severity and local resistance patterns 1
Important consideration: Unlike mild AOM in older children where watchful waiting may be appropriate, bullous myringitis is NOT a candidate for watchful waiting due to severe symptoms - parents will resist postponement of antibiotics, and the pain severity justifies immediate treatment. 2
Step 4: Systemic Corticosteroids
- Consider systemic corticosteroids in severe cases, particularly when sensorineural hearing loss is suspected 1
- This represents a key difference from standard AOM management
- Monitor for hearing changes during and after treatment
Monitoring and Follow-Up
Assess for sensorineural hearing loss:
- Perform audiometry if hearing concerns arise, as reversible cochlear involvement can occur 4, 5
- The hearing loss, when present, is typically transient but requires monitoring 1, 4
Expected clinical course:
- Symptoms typically resolve within 1-2 days in the majority of cases 3
- Short-term outcome is generally good despite initial severity 3
Critical Pitfalls to Avoid
Do not dismiss as simple AOM - the severity of symptoms and potential for complications (sensorineural hearing loss) warrant more aggressive management 1, 2
Do not attempt watchful waiting - even in older children who would otherwise be candidates, the pain severity makes this approach inappropriate 2
Do not overlook hearing assessment - while uncommon, sensorineural hearing loss can occur and requires identification and monitoring 1, 4, 5
Do not confuse with bullous pemphigoid or other bullous dermatoses - these are entirely different autoimmune conditions requiring immunosuppressive therapy, not antibiotics 6, 7, 8, 9