What is the effect of 2,4-Dinitrophenol (2,4-DNP) on the electron transport chain and ATP production in cellular respiration?

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From the Research

The statement that is NOT correct is B: "Cytochrome c does not accept electrons from Coenzyme Q". In reality, cytochrome c does accept electrons from Coenzyme Q through the mediation of Complex III (cytochrome bc1 complex) 1. The electron transport chain functions by transferring electrons through a series of carriers, with Coenzyme Q passing electrons to Complex III, which then transfers them to cytochrome c.

Key Points

  • The electron transport chain is located in the inner mitochondrial membrane.
  • Coenzyme Q accepts electrons from both Complex I and Complex II, as discussed in the context of Complex II ambiguities regarding FADH2 in the electron transfer system 1.
  • Complex IV (cytochrome oxidase) accepts electrons from cytochrome c.
  • Complex I is indeed called NADH dehydrogenase. This electron transfer pathway is essential for establishing the proton gradient that drives ATP synthesis through oxidative phosphorylation.

Electron Transport Chain Process

  • Electrons are passed through a series of carriers in the electron transport chain.
  • Coenzyme Q plays a crucial role in accepting electrons from Complex I and Complex II.
  • Cytochrome c acts as an intermediary, accepting electrons from Coenzyme Q via Complex III and then passing them to Complex IV. The accurate understanding of the electron transport chain process is vital for appreciating the role of cytochromes and other components in the generation of ATP during oxidative phosphorylation 1.

References

Research

Complex II ambiguities-FADH2 in the electron transfer system.

The Journal of biological chemistry, 2024

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