From the Research
Montelukast and Weight Gain
- There is limited evidence to suggest that montelukast (Singulair) causes weight gain.
- A case report from 1 describes a 22-year-old male patient who experienced unusual weight gain after 2 months of taking 10 mg oral montelukast daily for allergic rhinitis.
- However, this is a rare case and not a comprehensive study on the effects of montelukast on weight.
- Other studies, such as 2, 3, and 4, do not mention weight gain as a common side effect of montelukast.
- A study on the metabolic profiles of montelukast in human plasma and bile 5 does not provide information on weight gain.
Side Effects of Montelukast
- Common side effects of montelukast include sleep disturbance, agitation, pain, and hyperactivity, as reported in 4.
- Other studies, such as 2 and 3, report that montelukast is generally well-tolerated and effective in treating asthma and allergic rhinitis.
- A case report from 1 describes a rare case of montelukast-induced hypercholesterolemia, severe hypertriglyceridemia, and acute pancreatitis, which may be related to weight gain.