Clotrimazole Tube Size
Standard clotrimazole vaginal cream tubes contain 21 grams of medication. 1
Standard Packaging Information
- The FDA-approved clotrimazole 2% vaginal cream is packaged in a 21-gram (0.74 oz) tube 1
- This 21-gram tube size is standardized by the Centers for Disease Control and Prevention to provide sufficient medication for a complete treatment course based on the concentration and recommended duration of therapy 2
Dosing Context for the 21-Gram Tube
The 21-gram tube size corresponds to standard treatment regimens:
- For clotrimazole 2% cream: Apply 5g intravaginally for 3 days (total 15g needed), leaving adequate supply in the 21g tube 3, 2
- For clotrimazole 1% cream: Apply 5g intravaginally for 7-14 days, which may require multiple tubes for longer treatment courses 3, 2
Clinical Considerations
- The 21-gram tube with three disposable applicators is the standard commercial packaging for 3-day treatment regimens 1
- For extensive infections or longer treatment courses (10-14 days for complicated vulvovaginal candidiasis), multiple tubes may be required 2
- The oil-based formulation may weaken latex condoms and diaphragms 3, 2