Anterior Capsular Phimosis: Clinical Management
Anterior capsular phimosis (also called anterior capsular contraction syndrome) should be treated with Nd:YAG or femtosecond laser anterior capsulotomy when it causes decreased visual acuity, IOL decentration, or IOL tilt. 1
Pathophysiology and Risk Factors
Anterior capsular phimosis is caused by metaplastic lens epithelial cells leading to fibrosis and progressive shrinkage of the anterior capsular opening. 1
High-risk conditions include: 1
- Pseudoexfoliation syndrome
- Retinitis pigmentosa
- Diabetes mellitus
- Uveitis
- Eyes with zonular pathology
- Silicone IOL optic materials (higher risk than acrylic)
Clinical Presentation
- Progressive blurred vision
- Decreased visual acuity
- Visual distortion or metamorphopsia in severe cases
Signs on examination: 1, 2, 4, 3, 5
- Central anterior capsular opacification
- Visible shrinkage of the anterior capsular opening
- IOL decentration or tilt
- Haptic deformation or folding onto the optic (in severe cases)
- Fibrous membrane formation occluding the visual axis (in pseudoexfoliation patients)
- IOL dislocation in extreme cases
Diagnostic Approach
Slit-lamp examination findings: 3, 5
- Co-axial retro-illumination reveals capsular scarring and contraction
- Assessment of IOL position and stability
- Evaluation of anterior chamber inflammation
Anterior segment optical coherence tomography (ASOCT) can confirm the diagnosis and assess severity of capsular contraction and IOL deformation. 3, 5
Fundus examination may be difficult due to media haze from capsular scarring but should be attempted to rule out posterior segment pathology. 3
Treatment Algorithm
Primary Treatment: Laser Capsulotomy
Nd:YAG or femtosecond laser anterior capsulotomy is the first-line treatment for anterior capsular phimosis. 1
Pre-procedure requirements: 1, 6
- Ensure the eye is inflammation-free
- Confirm IOL stability
- Assess for risk factors (glaucoma, axial myopia, vitreoretinal disease)
Post-procedure monitoring: 1
- Monitor IOP in the early postoperative period, especially in high-risk patients
- Consider prophylactic IOP-lowering agents in patients with pre-existing glaucoma
- Treatment with topical corticosteroid, NSAID, ocular hypotensive, or cycloplegic agents depends on patient risk factors
Alternative Surgical Technique
For cases requiring vitreoretinal surgery or when laser capsulotomy is insufficient, a surgical approach using fine pointed scissors to cut the anterior capsule radially toward the optic edge, followed by capsulorrhexis forceps to tear away the anterior capsule, has been described as effective. 2
Severe Cases Requiring IOL Exchange
In cases of severe capsular bag phimosis with significant IOL deformation that would result in severe image distortion, metamorphopsia, and aniseikonia even after YAG capsulotomy, IOL explantation with the phimosed capsular bag and placement of a scleral-fixated IOL may be necessary. 3
Prevention Strategies
Anterior capsule polishing during initial cataract surgery may reduce the incidence of anterior capsular phimosis. 1
However, avoid anterior capsule polishing if posterior capsule rupture occurs, as this may destabilize remaining capsular support. 7
Important Complications and Patient Education
Complications of laser anterior capsulotomy include: 1
- Increased IOP (most common)
- Retinal detachment (0.87% risk in first 5 months)
- Retinal tear (0.29% risk in first 5 months)
- Cystoid macular edema
- IOL damage or dislocation
- Persistent floaters
Patient education is critical: 1, 6
- Educate high-risk patients about symptoms of retinal tears or detachment (new floaters, flashes, visual field defects) to facilitate early diagnosis
- Eyes with axial length less than 24.0 mm have shown 0% incidence of retinal detachment in case series
Clinical Outcomes
YAG laser anterior capsulotomy leads to good visual outcomes with low complication rates, with studies showing comparable results whether performed by experienced ophthalmologists or appropriately trained advanced practitioners. 8