Radiological Findings of Glomus Jugulare
High-resolution CT temporal bone demonstrates irregular lytic bone destruction with enlargement of the jugular foramen, while MRI with contrast reveals a hypervascular soft tissue mass with characteristic "salt-and-pepper" appearance, and angiography shows intense tumor blush supplied predominantly by the ascending pharyngeal artery. 1
CT Temporal Bone Findings
Osseous Changes
- Irregular lytic bone destruction with enlargement of the jugular foramen is the hallmark CT finding that distinguishes glomus jugulare from benign lesions like schwannomas, which show smooth, well-defined bone margins 1
- CT demonstrates superior sensitivity (87.5%) for detecting hypoglossal canal invasion compared to MRI, making it essential for surgical planning 2
- Thin-cut high-resolution bone windows through the posterior skull base are required to adequately assess the extent of bony involvement 2
Key Distinguishing Features
- Unlike glomus tympanicum (which shows soft tissue on the promontory without bone erosion), glomus jugulare demonstrates frank erosion of the jugular foramen and often the carotid canal 3
- The bony reconstructions from CTA can provide excellent osseous detail and may be more accurate than MRI for diagnosing glomus jugulare in some studies 2
MRI Findings
Soft Tissue Characterization
- MRI with contrast is essential for evaluating the full extent of glomus jugulare, particularly intracranial extension and involvement of adjacent soft tissue structures 3
- MRI demonstrates 100% sensitivity for detecting hypoglossal canal invasion, though with lower specificity (59%) compared to CT 2
- The improved soft tissue contrast allows assessment of the brainstem, intracranial nerve segments, and extracranial nerve course 2
Vascular Assessment
- MRA with contrast can detect larger glomus jugulare tumors and assess intracranial vascular involvement 3
- MRI reveals vascular and soft tissue structures to best advantage compared to CT 1
Angiographic Findings
Vascular Supply Pattern
- The inferior tympanic artery (branch of the ascending pharyngeal artery) provides the dominant blood supply to glomus jugulare tumors 3
- Angiography demonstrates a hypervascular lesion with intense tumor blush supplied by numerous small branches of the external carotid artery system 4
- Tumors may receive supplementary blood supply from clival branches of the internal carotid artery when extending around the carotid canal 3
Pre-procedural Mapping Requirements
- Selective catheterization of both external and internal carotid branches is required to adequately delineate the complete blood supply 3
- Superselective catheterization of external carotid branches confirms blood supply and reveals dangerous intracranial anastomoses that must be identified before embolization 3
- Evaluation of contralateral carotid branches is necessary to exclude contribution to tumor blush, particularly when tumor crosses midline 3
- Digital subtraction angiography allows identification of displaced feeders, facilitating their localization for potential surgical ligation 3
Imaging Protocol Recommendations
First-Line Imaging
- CTA head and neck with IV contrast is the imaging modality of choice because it demonstrates both arterial and venous pathologies while providing excellent bony detail from thin-section reconstructions 2
- CTA has combined sensitivity and specificity of 90% for detecting vascular pathology and can diagnose glomus jugulare more accurately than MRI in some studies 2
Complementary Studies
- High-resolution CT temporal bone without contrast provides superior osseous detail but cannot assess vascular abnormalities 2
- MRI with contrast serves as the confirmatory study and is essential for evaluating intracranial extension 3
Critical Clinical Pitfalls
Biopsy Contraindication
- Never perform biopsy of suspected glomus tumors due to risk of devastating hemorrhagic complications—imaging alone establishes the diagnosis 3
- Several non-paraganglioma lesions (hemangiopericytoma, extramedullary plasmacytoma, giant cell tumors) can mimic glomus jugulare in clinical and radiographic presentation, but the hypervascularity visible on imaging should preclude blind biopsy 4, 5