How does a cholesteatoma affect the results of an audiogram in a patient?

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Cholesteatoma Effect on Audiogram

Cholesteatoma characteristically produces a conductive hearing loss on audiogram, with the air-bone gap reflecting the degree of ossicular chain erosion and middle ear involvement. 1, 2

Audiometric Pattern

  • Conductive hearing loss is the hallmark finding, manifesting as an air-bone gap where bone conduction thresholds remain normal while air conduction thresholds are elevated 2, 3

  • The air-bone gap directly correlates with the extent of ossicular damage, with more severe gaps indicating greater ossicular erosion 2, 4

  • Preoperative hearing levels are typically worse in patients with advanced disease requiring canal wall down procedures compared to those with limited disease amenable to intact canal wall techniques 2

Frequency-Specific Characteristics

  • Hearing loss is most pronounced at frequencies between 500-3,000 Hz, which are critical for speech understanding 2

  • Unlike Ménière's disease which shows low-to-mid frequency sensorineural hearing loss, cholesteatoma produces conductive loss across frequencies 5

  • Sensorineural hearing loss is not typically caused by cholesteatoma unless there is erosion into the inner ear structures (lateral semicircular canal involvement) 2

Disease-Specific Variations

  • Attic cholesteatomas tend to have better hearing outcomes compared to other locations, likely due to less extensive ossicular involvement 2

  • Children demonstrate worse preoperative and postoperative hearing levels compared to adolescents or adults, with recurrence rates of 13% versus 10% in adults 6, 2

  • Congenital cholesteatoma may present with progressive conductive hearing loss and a completely normal-appearing tympanic membrane, making it challenging to diagnose without imaging 4, 3

Progressive Nature

  • Progressive conductive hearing loss with an intact tympanic membrane and soft tissue density in the middle ear on CT should raise high suspicion for open-type congenital cholesteatoma 3

  • Bilateral cholesteatoma results in worse total postoperative hearing compared to unilateral disease 2

  • Revision operations and recurrent cholesteatoma are associated with significantly worse hearing outcomes for all analyzed parameters 2

Critical Diagnostic Pitfall

Do not confuse cholesteatoma with sensorineural hearing loss conditions—the presence of an air-bone gap with normal bone conduction distinguishes it from retrocochlear lesions like vestibular schwannoma, which typically show mid-to-high frequency sensorineural loss (especially at 3000 Hz) with minimal fluctuation 5

References

Guideline

Cholesteatoma Diagnosis and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Audiologic results of surgery for cholesteatoma: short- and long-term follow-up of influential factors.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2008

Research

Congenital cholesteatoma: predictors for residual disease and hearing outcomes.

Archives of otolaryngology--head & neck surgery, 2012

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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