From the FDA Drug Label
The most common side effects of TRINTELLIX include nausea, constipation, and vomiting. Ingestion of TRINTELLIX in the dose range of 40 to 75 mg was associated with increased rates of nausea, dizziness, diarrhea, abdominal discomfort, generalized pruritus, somnolence, and flushing. The most frequently reported symptoms with overdoses up to 80 mg (four times the maximum recommended daily dose) were nausea and vomiting Discontinuation syndrome. Suddenly stopping TRINTELLIX may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly Symptoms may include: nausea
Yes, Trintellix (vortioxetine) can cause:
- Nausea: as a common side effect, with increased rates at higher doses, and as a symptom of discontinuation syndrome.
- Dysphagia: is not mentioned in the provided drug labels.
- Anorexia: is not mentioned in the provided drug labels as a side effect, but decreased appetite can be associated with nausea and vomiting. 1, 1, 1
From the Research
Side Effects of Trintellix (Vortioxetine)
- Nausea is a common side effect of Trintellix, as reported in studies 2, 3, 4, 5
- Dysphagia is not explicitly mentioned as a side effect in the provided studies
- Anorexia is mentioned as a potential side effect in one study 6, which discusses gastrointestinal side effects associated with antidepressant treatments, including vortioxetine
Gastrointestinal Side Effects
- Vortioxetine is associated with various gastrointestinal side effects, including nausea, vomiting, diarrhea, and constipation 2, 3, 6, 5
- The drug may have a different profile of gastrointestinal side effects compared to other antidepressants, potentially related to its mechanism of action 6