What is the cause of a red streak from a skin infection, specifically a sign of lymphangitis?

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Last updated: April 19, 2025View editorial policy

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Differential Diagnosis for Red Streak from Infection

  • Single most likely diagnosis
    • Cellulitis: This is the most likely diagnosis, as a red streak is a common presentation of cellulitis, which is a bacterial skin infection that can cause redness, swelling, and warmth of the skin.
  • Other Likely diagnoses
    • Erysipelas: This is a type of skin infection that can cause a red, raised, and well-defined streak, often accompanied by fever and swelling.
    • Lymphangitis: This is an infection of the lymphatic vessels, which can cause a red streak that follows the path of the lymphatic vessels, often accompanied by fever and swelling.
    • Phlebitis: This is an inflammation of the veins, which can cause a red streak along the path of the affected vein, often accompanied by warmth, swelling, and pain.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Necrotizing fasciitis: This is a life-threatening infection that can cause a red streak, but it is often accompanied by severe pain, swelling, and crepitus (a crunching feeling under the skin).
    • Gas gangrene: This is a life-threatening infection that can cause a red streak, but it is often accompanied by severe pain, swelling, and crepitus, as well as a foul odor.
  • Rare diagnoses
    • Erythema migrans (Lyme disease): This is a rare diagnosis that can cause a red streak, but it is often accompanied by a distinctive "bull's-eye" rash and flu-like symptoms.
    • Sweet syndrome: This is a rare diagnosis that can cause a red streak, but it is often accompanied by fever, swelling, and a distinctive neutrophilic infiltrate on biopsy.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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